2-(2-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide

2-(2-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide 基本信息
CAS号 6101-04-8 分子式 C20H14ClN3O3
分子量 379.79600 精确质量  379.07200
PSA  80.74000 LogP  5.21020

基本信息 展开↓

CAS号:
6101-04-8
3D弹球模型:
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分子式:
C20H14ClN3O3
分子量:
379.79600
中文名称:
2-(2-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
英文名称:
2-(2-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
中文别名:
2-(2-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
英文别名:
2-(2-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide;
Strychnin,Hydrochlorid;
strychnine,hydrochloride;
2-(2-chlorophenoxy)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]acetamide
精确分子量/精确质量:
379.07200
极性分子表面积/PSA:
80.74000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
InChI:
The Key: VMFWMHJDVHIGPD-UHFFFAOYSA-N

物化性质展开↓

密度:
1.398g/cm3
沸点:
626.4ºC at 760 mmHg
闪点:
332.6ºC
折射率:
1.679

MSDS 展开↓


Section 1. Chemical Product and Company Identification
    Strychnine HCl dihydrate        Catalog    
    ST145
    Common Name/
    Number(s).
    Trade Name
    CAS#        6101-04-8    
    Manufacturer
    RTECS        WL2430000    
    SPECTRUM QUALITY PRODUCTS INC.
    TSCA        TSCA 8(b) inventory:    
    Strychnine HCl dihydrate
    Commercial Name(s)        Not available.    
    CI# Not available.
    Synonym        Strychnidin-10-one hydrochloride    
    IN CASE OF EMERGENCY
    Strychnine Hydrochloride
    Chemical Name
    Chemical Family        Not available.        CALL (310) 516-8000    
    (C21H22N2O2)2.HCl.2H2O
    Chemical Formula
    SPECTRUM QUALITY PRODUCTS INC.

Section 2.Composition and Information on Ingredients
    Exposure Limits
    TWA (mg/m3)        STEL (mg/m3) CEIL (mg/m3)    
    Name        CAS #        % by Weight    
    1) Strychnine HCl dihydrate        6101-04-8        100    
    Toxicological Data        Strychnine HCl dihydrate:    
    on Ingredients        ORAL (LD50):        Acute: 2 mg/kg [Rat].    

Section 3. Hazards Identification
    Potential Acute Health Effects Extremely hazardous in case of inhalation. Very hazardous in case of eye contact (irritant), of ingestion.
    Hazardous in case of skin contact (irritant). Severe over-exposure can result in death. Inflammation of the eye is
    characterized by redness, watering, and itching.
    Potential Chronic Health        CARCINOGENIC EFFECTS: Not available.    
    Effects        MUTAGENIC EFFECTS: Not available.    
    TERATOGENIC EFFECTS: Not available.
    DEVELOPMENTAL TOXICITY: Not available.
    The substance is toxic to the nervous system.
    The substance may be toxic to heart, central nervous system (CNS).
    Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure to a
    highly toxic material may produce general deterioration of health by an accumulation in one or many human
    organs.
    Strychnine HCl dihydrate

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at    
    least 15 minutes. Cold water may be used. Get medical attention immediately.
    Skin Contact        In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove    
    contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes
    before reuse. Get medical attention.
    Serious Skin Contact        Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate    
    medical attention.
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or    
    waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
    resuscitation. Seek medical attention.
    Ingestion        If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by    
    mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
    attention immediately.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.    
    Fire Hazards in Presence of Not available.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    Risks of explosion of the product in presence of static discharge: Not available.
    of Various Substances
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Special Remarks on        Not available.    
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container.    
    Large Spill
    Poisonous solid.
    Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to
    reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition
    Strychnine HCl dihydrate

Section 7. Handling and Storage
    Precautions        Keep locked up.. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk,    
    evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not
    breathe dust. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical
    advice immediately and show the container or the label. Avoid contact with skin and eyes.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area.    

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.    
    Gloves.
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist    
    BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Powdered solid.)        Odor        Odorless.    
    Bitter.
    Taste
    Molecular Weight        406.9 g/mole    
    White.
    Color
    Not available.
    pH (1% soln/water)
    Boiling Point        Not available.    
    Melting Point        Decomposes.    
    Critical Temperature        Not available.    
    Specific Gravity        Not available.    
    Not applicable.
    Vapor Pressure
    Vapor Density        Not available.    
    Not available.
    Volatility
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Ionicity (in Water)        Not available.    
    Dispersion Properties        See solubility in water.    
    Solubility        Partially soluble in cold water.    

Section 10. Stability and Reactivity Data
    Stability        The product is stable.    
    Instability Temperature        Not available.    
    Conditions of Instability        Not available.    
    Incompatibility with various        Not available.    
    substances
    Corrosivity        Non-corrosive in presence of glass.    
    Strychnine HCl dihydrate
    Special Remarks on        Not available.    
    Reactivity
    Special Remarks on        Not available.    
    Corrosivity
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Absorbed through skin. Eye contact. Inhalation. Ingestion.    
    Toxicity to Animals        Acute oral toxicity (LD50): 2 mg/kg [Rat].    
    Chronic Effects on Humans        Causes damage to the following organs: the nervous system.    
    May cause damage to the following organs: heart, central nervous system (CNS).
    Other Toxic Effects on        Extremely hazardous in case of inhalation.    
    Humans        Very hazardous in case of ingestion.    
    Hazardous in case of skin contact (irritant).
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        Not available.    
    Chronic Effects on Humans
    Special Remarks on other        Not available.    
    Toxic Effects on Humans

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    Not available.
    BOD5 and COD
    Possibly hazardous short term degradation products are not likely. However, long term degradation products may
    Products of Biodegradation
    arise.
    Toxicity of the Products        The products of degradation are less toxic.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste Disposal

Section 14. Transport Information
    DOT Classification        CLASS 6.1: Poisonous material.    
    Identification        : Strychnine salt (Strychnine hydrochloride) UNNA: 1692 PG: I    
    Marine Pollutant
    Special Provisions for
    Transport
    Strychnine HCl dihydrate
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    TSCA 8(b) inventory: Strychnine HCl dihydrate
    Federal and State
    SARA 302/304/311/312 extremely hazardous substances: Strychnine HCl dihydrate
    Regulations
    California
    Proposition 65
    Warnings
    Other Regulations        OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).    
    CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
    Other Classifications        WHMIS (Canada)    
    CLASS D-2B: Material causing other toxic effects (TOXIC).
    DSCL (EEC)        R28- Very toxic if swallowed.    
    R38- Irritating to skin.
    R41- Risk of serious damage to eyes.
    Health Hazard
    HMIS (U.S.A.)        3 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    3 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Strychnine HCl dihydrate
    Dust respirator. Be sure to use an
    approved/certified respirator or
    equivalent. Wear appropriate respirator
    when ventilation is inadequate.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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