cas号： 107-49-3 ，名称：特普的性质/作用/用途-化学加百科

特普

特普基本信息
CAS号	107-49-3	分子式	C8H20O7P2
分子量	290.18924	精确质量	290.06843
PSA	99.91000	LogP	3.36520

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基本信息制备方法与用途物化性质安全信息合成路线化学图谱毒性 MSDS 结构与计算数据上下游

基本信息展开↓

CAS号：: 107-49-3
3D弹球模型：: 立即前往扯扯看
分子式：: C8H20O7P2
分子量：: 290.18924
中文名称：: 特普
英文名称：: Diphosphoric acid, P,P,P',P'-tetraethyl ester
中文别名：: 特普;
双-O,O-二乙基磷酸酐;
死虫四磷;
四乙基焦磷酸酯;
焦磷酸四乙酯
英文别名：: Diphosphoric acid, P,P,P',P'-tetraethyl ester;
Diphosphoric acid, tetraethyl ester (9CI);
Pyrophosphoric acid, tetraethyl ester (8CI);
Bis-O,O-diethylphosphoric anhydride;
Bladan;
Ethyl pyrophosphate (Et4P2O7);
Killex;
NSC 14707;
NSC 646213;
Nifos;
Pyrodust;
TEP;
TEP (phosphate);
TEPP;
Tetraethyl diphosphate;
Tetraethyl pyrophosphate;
Tetrastigmine;
Vapotone
精确分子量/精确质量：: 290.06843
极性分子表面积/PSA：: 99.91000
油水分配系数/LogP：: LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值，反映了物质在油水两相中的分配情况。其中、LogP值越大，说明该物质越亲油；反之，LogP值越小，则说明该物质越亲水。
贝尔斯坦号/MDL：: MFCD00055459
EINECS：: 203-495-3
PubChem：: 24862556
BRN：: 1714017
InChI：: The Key: IDCBOTIENDVCBQ-UHFFFAOYSA-N

生产制备方法及用途展开↓

制备方法

用作农用杀蚜、杀螨剂。

用途简介

用途

用作农用杀蚜、杀螨剂。

物化性质展开↓

密度：: 1.205 g/cm3
沸点：: 260.9ºC at 760 mmHg
闪点：: >100 °C
折射率：: 1.425
蒸汽压：: 0.0193mmHg at 25°C
存储条件/存储方法：: 库房通风低温干燥,与食品原料分开储运
稳定性相关：: 避免与强碱、水、潮湿空气接触。
其它信息：: 1.      性状：无色无味吸湿性液体。
2.      密度（g/mL,25℃）：1.185
3.      相对蒸汽密度（g/mL,空气=1）：未确定
4.      熔点（ºC）：未确定
5.      沸点（ºC,常压）：
6.      沸点（ºC, 0.133kPa）：124
7.      折射率（_D²⁰)：未确定
8.      闪点（ºC）：未确定
9.      比旋光度（ºC）：未确定
10.   自燃点或引燃温度（ºC）: 未确定
11.   蒸气压（mmHg, 20ºC）：未确定
12.   饱和蒸气压（kPa, 20ºC）：0.206×10-4
13.   燃烧热（KJ/mol）：未确定
14.   临界温度（ºC）：未确定
15.   临界压力（KPa）：未确定
16.   油水（辛醇/水）分配系数的对数值：未确定
17.   爆炸上限（%,V/V）：未确定
18.   爆炸下限（%,V/V）：未确定
19.   溶解性：与水混溶，可混溶于多数有机溶剂。

安全信息展开↓

包装等级：: I
风险类别：: 6.1(a)
海关代码：: 2919900035
危险类别码：: 27/28-50
安全说明：: S36/37/39-S38-S45-S61
RTECS号：: UX6825000
安全标志：: S38:在通风不良的场所，佩戴合适的呼吸装置。
S45:出现意外或者感到不适，立刻到医生那里寻求帮助（最好带去产品容器标签）。
S61:避免排放到环境中。参考专门的说明/安全数据表。
:
危险标志：: T+,N

合成路线查看所有的合成路线

26905-48-6

26905-48-6
→

~95%
107-49-3

特普

4972-37-6

4972-37-6
+
5802-76-6

N,N-diethylethanamine
→

~92%
107-49-3

特普

598-02-7

磷酸二乙酯
+
814-49-3

氯磷酸二乙酯
→

~91%
107-49-3

特普

化学图谱

二磷酸四乙酯质谱(MS)

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UX6825000

CHEMICAL NAME :: Pyrophosphoric acid, tetraethyl ester

CAS REGISTRY NUMBER :: 107-49-3

BEILSTEIN REFERENCE NO. :: 1714017

LAST UPDATED :: 199806

DATA ITEMS CITED :: 55

MOLECULAR FORMULA :: C8-H20-O7-P2

MOLECULAR WEIGHT :: 290.22

WISWESSER LINE NOTATION :: 2OPO&O2&OPO&O2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 1429 ug/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - paresthesis Behavioral - excitement Gastrointestinal - nausea or vomiting

REFERENCE :: CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956 Volume(issue)/page/year: -,1,1956

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 309 ug/kg

TOXIC EFFECTS :: Behavioral - wakefulness Behavioral - muscle contraction or spasticity Gastrointestinal - other changes

REFERENCE :: CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956 Volume(issue)/page/year: -,1,1956

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Human

DOSE/DURATION :: 286 ug/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - paresthesis Behavioral - excitement Gastrointestinal - nausea or vomiting

REFERENCE :: CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956 Volume(issue)/page/year: -,1,1956

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 71 ug/kg

TOXIC EFFECTS :: Behavioral - wakefulness Behavioral - muscle contraction or spasticity Gastrointestinal - other changes

REFERENCE :: CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956 Volume(issue)/page/year: -,1,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHJOAV Pharmaceutical Journal. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London, SE1 7JN, UK) V.131- 1933- Volume(issue)/page/year: 185,361,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2400 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 14,515,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 650 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 6,353,1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 279 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S195,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 ug/kg

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases

REFERENCE :: CJBPAZ Canadian Journal of Biochemistry and Physiology. (Ottawa, Ont., Canada) V.32-41, 1954-63. For publisher information, see CJBIAE. Volume(issue)/page/year: 34,197,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1800 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JCINAO Journal of Clinical Investigation. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1924- Volume(issue)/page/year: 37,350,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1120 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971 Volume(issue)/page/year: -,379,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 27,684,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 27,684,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 830 ug/kg

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 121,104,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 29,875,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,299,1954

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 17 uL/kg

TOXIC EFFECTS :: Behavioral - excitement Gastrointestinal - changes in structure or function of salivary glands Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534856

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IAEC** Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974 Volume(issue)/page/year: 17JUN1974

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 300 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Cardiac - pulse rate Lungs, Thorax, or Respiration - other changes

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 8,466,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 53,512,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2300 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 105,156,1952

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 14,5,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Bird - pigeon

DOSE/DURATION :: 180 ug/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Sense Organs and Special Senses (Eye) - effect, not otherwise specified

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 102,371,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 3560 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 47,451,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 64 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 47,451,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 34 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - other changes

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 124,212,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 1300 ug/kg

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972 *** REVIEWS *** ACGIH TLV-TWA 0.047 mg/m3 (0.004 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW CRTXB2 CRC Critical Reviews in Toxicology. (CRC Press, Inc., 2000 Corporate Blvd., NW, Boca Raton, FL 33431) V.1- 1971- Volume(issue)/page/year: 3,289,1975 TOXICOLOGY REVIEW AQMOAC Air Quality Monographs. (Washington, DC) No.69-1 - No.75-25, 1969-75(?). Discontinued. Volume(issue)/page/year: #73-19,1973 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973 TOXICOLOGY REVIEW IRXPAT International Review of Experimental Pathology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1962- Volume(issue)/page/year: 3,219,1964 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.004 ppm (0.05 mg/m3) DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,28,1973 OSHA PEL (Gen Indu):8H TWA 0.05 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.05 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.05 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.05 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.004 ppm (0.05 mg/m3);Skin JAN 1993 OEL-AUSTRALIA:TWA 0.004 ppm (0.05 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 0.004 ppm (0.047 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 0.004 ppm (0.05 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 0.004 ppm (0.05 mg/m3);Skin JAN 1993 OEL-GERMANY:TWA 0.005 ppm (0.05 mg/m3);Skin JAN 1993 OEL-THE NETHERLANDS:TWA 0.004 ppm (0.05 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.05 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.005 ppm (0.05 mg/m3);Skin JAN 1993 OEL-TURKEY:TWA 0.05 mg/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.004 ppm (0.05 mg/m3);STEL 0.01 ppm (0.2 mg/m3);Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO TEPP-air:10H TWA 0.05 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 71680 No. of Facilities: 9 (estimated) No. of Industries: 1 No. of Occupations: 14 No. of Employees: 1434 (estimated)

毒理学数据：

1、急性毒性：大鼠经口LD5O：0.5mg/kg

兔经皮LD5O：2.4mg/kg

小鼠经口LD5O：0.5mg/kg

生态数据：

该物质对环境可能有危害，建议不要让其进入环境。

MSDS 展开↓

第一部分：化学品名称

化学品中文名称：	特普；焦磷酸四乙酯
化学品英文名称：	TEPP；Tetraethyl pyrophosphate
中文俗名或商品名：
Synonyms：
CAS No.：	107-49-3
分子式：	C₈H₂₀O₇P₂
分子量：	290.22

第二部分：成分/组成信息

纯化学品混合物

化学品名称：特普；焦磷酸四乙酯

有害物成分

含量

CAS No.

第三部分：危险性概述

危险性类别：	第6．1类毒害品
侵入途径：	吸入食入经皮吸收
健康危害：	本品为高毒有机磷杀虫剂，抑制胆碱酯酶活性。轻度中毒表现有头痛、头晕、多汗、流涎、视力模糊、乏力、恶心、呕吐和胸闷；中度中毒以肌束震颤为特征，出现瞳孔缩小、呼吸困难、大汗、腹痛、神志模糊等症状；重度中毒出现昏迷、惊厥、肺水肿、呼吸抑制和脑水肿等。
环境危害：	对环境有危害。
燃爆危险：

第四部分：急救措施

皮肤接触：	脱去污染的衣物，用肥皂水及清水彻底冲洗。就医。
眼睛接触：	拉开眼睑，用流动清水冲洗15分钟。就医。
吸入：	脱离现场至空气新鲜处。呼吸困难时给输氧。呼吸停止时，立即进行人工呼吸。合并使用阿托品及复能剂(氯磷定、解磷定)。
食入：	误服者，饮适量温水，催吐。洗胃。就医。合并使用阿托品及复能剂(氯磷定、解磷定)。

第五部分：消防措施

危险特性：	遇明火、高热可燃。受高热分解，放出有毒的烟气。
有害燃烧产物：
灭火方法及灭火剂：	泡沫、干粉、砂土。
消防员的个体防护：
禁止使用的灭火剂：
闪点(℃)：
自燃温度(℃)：
爆炸下限[%(V/V)]：
爆炸上限[%(V/V)]：
最小点火能(mJ)：
爆燃点：
爆速：
最大燃爆压力(MPa)：
建规火险分级：

第六部分：泄漏应急处理

应急处理：

疏散泄漏污染区人员至安全区，禁止无关人员进入污染区，建议应急处理人员戴自给式呼吸器，穿化学防护服。不要直接接触泄漏物，喷雾状水，减少蒸发。用砂土或其它不燃性吸附剂混合吸收，收集于一个密闭的容器中，运至废物处理场所。也可以用不燃性分散剂制成的乳液刷洗，经稀释的洗水放入废水系统。如大量泄漏，利用围堤收容，然后收集、转移、回收或无害处理后废弃。

第七部分：操作处置与储存

操作注意事项：
储存注意事项：

第八部分：接触控制/个体防护

最高容许浓度：	中国 MAC：未制订标准前苏联MAC：未制订标准美国TLV—TWA：0．004mg／m
监测方法：
工程控制：	严加密闭，提供充分的局部排风。尽可能机械化、自动化。
呼吸系统防护：	可能接触其蒸气时，应该佩戴防毒面具。紧急事态抢救或逃生时，佩戴自给式呼吸器。
眼睛防护：	戴化学安全防护眼镜。
身体防护：	穿化学防护服。
手防护：	戴防化学品手套。
其他防护：	工作现场禁止吸烟、进食和饮水。工作后，淋浴更衣。工作服不要带到非作业场所，单独存放被毒物污染的衣服，

第九部分：理化特性

外观与性状：	无色无味吸湿性液体。
pH：
熔点(℃)：
沸点(℃)：	124／0．133kPa
相对密度(水=1)：	1．185
相对蒸气密度(空气=1)：
饱和蒸气压(kPa)：	0．206×10(-4)／20℃
燃烧热(kJ/mol)：
临界温度(℃)：
临界压力(MPa)：
辛醇/水分配系数的对数值：
闪点(℃)：
引燃温度(℃)：
爆炸上限%(V/V)：
爆炸下限%(V/V)：
分子式：	C₈H₂₀O₇P₂
分子量：	290.22
蒸发速率：
粘性：
溶解性：	与水混溶，可混溶于多数有机溶剂。
主要用途：	农用杀蚜、杀螨剂。

第十部分：稳定性和反应活性

稳定性：	在常温常压下稳定
禁配物：	强碱、水、潮湿空气。
避免接触的条件：
聚合危害：	不能出现
分解产物：	一氧化碳、二氧化碳、氧化磷、磷化氢。

第十一部分：毒理学资料

急性毒性：	LD50：0．5mg／kg(大鼠经口)；7mg／kg(小鼠经口)；2．4mg／kg(兔经皮) LC50：
急性中毒：
慢性中毒：
亚急性和慢性毒性：
刺激性：
致敏性：
致突变性：
致畸性：
致癌性：

第十二部分：生态学资料

生态毒理毒性：
生物降解性：
非生物降解性：
生物富集或生物积累性：

第十三部分：废弃处置

废弃物性质：
废弃处置方法：
废弃注意事项：

第十四部分：运输信息

危险货物编号：	61126
UN编号：	3018
包装标志：
包装类别：	Ⅰ
包装方法：
运输注意事项：	储存于阴凉、通风仓间内。严禁火种，应严格执行极毒物品“五双”管理制度。保持容器密封。防止受潮和雨淋。应与碱类、潮湿物品等分开存放。不能与粮食、食物、种子、饲料、各种日用品混装、混运。操作现场不得吸烟、
RETCS号：
IMDG规则页码：

第十五部分：法规信息

国内化学品安全管理法规：
国际化学品安全管理法规：

第十六部分：其他信息

参考文献：	1.周国泰，化学危险品安全技术全书，化学工业出版社，1997 2.国家环保局有毒化学品管理办公室、北京化工研究院合编，化学品毒性法规环境数据手册，中国环境科学出版社.1992 3.Canadian Centre for Occupational Health and Safety,CHEMINFO Database.1998 4.Canadian Centre for Occupational Health and Safety, RTECS Database, 1989
填表时间：	年月日
填表部门：
数据审核单位：
修改说明：
其他信息：	6
MSDS修改日期：	年月日

分子结构与计算化学数据展开↓

分子结构数据

1、摩尔折射率：61.58

2、摩尔体积（cm³/mol）：240.6

3、等张比容（90.2K）：592.9

4、表面张力（dyne/cm）：36.8

5、极化率（10-24cm3）：24.41

计算化学数据

1.疏水参数计算参考值（XlogP）:0.4

2.氢键供体数量:0

3.氢键受体数量:7

4.可旋转化学键数量:10

5.互变异构体数量:无

6.拓扑分子极性表面积80.3

7.重原子数量:17

8.表面电荷:0

9.复杂度:246

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

上下游相关产品

上游产品

814-49-3

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762-04-9

亚磷酸二乙酯
645-78-3

硫代-四乙基焦磷酸酯
26905-48-6

N/A
598-02-7

磷酸二乙酯

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4697-37-4

ethyl metaphosphate
5630-71-7

Chloroethyl diethyl phosphate
54509-73-8

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特普

基本信息 展开↓