CHEMICAL IDENTIFICATION

RTECS NUMBER :

ZA4870000

CHEMICAL NAME :

Virginiamycin S1, 4-(4(dimethylamino)-N-methyl-L-phenylalanine)-

CAS REGISTRY NUMBER :

3131-03-1

BEILSTEIN REFERENCE NO. :

0078387

LAST UPDATED :

199706

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C45-H54-N8-O10

MOLECULAR WEIGHT :

867.07

WISWESSER LINE NOTATION :

T F5-19-6 ANV DNV JNV MMV QOV TMV A&VTJ C1R DN1&1& D1 L2 P1 SR& OMV- BT6NJ CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

200 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967 Volume(issue)/page/year: -,750,1967

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

350 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 1,367,1978

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

200 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967 Volume(issue)/page/year: -,750,1967