CHEMICAL IDENTIFICATION

RTECS NUMBER :

UR6475100

CHEMICAL NAME :

3(2H)-Pyridazinone, 4,5-dihydro-6-(2-(4-pyridinyl)ethenyl)-, (E)-

CAS REGISTRY NUMBER :

87164-90-7

LAST UPDATED :

199403

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C11-H11-N3-O

MOLECULAR WEIGHT :

201.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

7 gm/kg/28D-I

TOXIC EFFECTS :

Vascular - BP lowering not characterized in autonomic section Nutritional and Gross Metabolic - body temperature decrease Related to Chronic Data - death

REFERENCE :

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 14,797,1990

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

45500 mg/kg/26W-I

TOXIC EFFECTS :

Vascular - structural changes in vessels Vascular - other changes Related to Chronic Data - death

REFERENCE :

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 14,797,1990