核黄素磷酸钠

核黄素磷酸钠 基本信息
CAS号 6184-17-4 分子式 C17H23N4Na2O11P
分子量 536.33800 精确质量  536.09000
PSA  242.02000 LogP  -0.81040

基本信息 展开↓

CAS号:
6184-17-4
3D弹球模型:
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分子式:
C17H23N4Na2O11P
分子量:
536.33800
中文名称:
核黄素磷酸钠
英文名称:
RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE
中文别名:
核黄素磷酸钠;
核黄素-5'-磷酸钠盐,二水合物;
核黄素-5’-磷酸钠二水合物;
核黄素-5'-磷酸钠盐水合物;
核黄素-5'-磷酸钠盐,二水
英文别名:
RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE;
FMN MONOSODIUM SALT DIHYDRATE;
O5'-phosphono-riboflavin,monosodium-salt;
FMN SODIUM SALT,DIHYDRATE;
O5'-Phosphono-riboflavin,Mononatrium-Salz,sodium salt;
RIBOFLAVIN SODIUM PHOSPHATE;
FLAVINMONONUCLEOTIDE DIHYDRATE;
FMN;
FMN,DIHYDRATE;
Phosphated Riboflavin;
FMM-NA 2H2O;
FMN-NA DIHYDRATE;
FMN-Na
精确分子量/精确质量:
536.09000
极性分子表面积/PSA:
242.02000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
贝尔斯坦号/MDL:
MFCD00150993
EINECS:
204-988-6
PubChem:
24894817
BRN:
4106529
InChI:
The Key: BHRVCJBIICJWTH-APQIITSESA-M

生产制备方法及用途展开↓

制备方法


维生素类药,用于治疗各种VB2缺乏症,同时也可大量用作食品添加剂

用途简介


物化性质展开↓

外观与性状:
淡黄色结晶粉末
熔点:
>300°C
存储条件/存储方法:

2-8℃ 避光,阴凉干燥处,密封保存  

稳定性相关:

常温常压下稳定,黄色晶体

其它信息:

1.       性状:黄色晶体

2.       密度(g/mL,25):未确定

3.       相对蒸汽密度(g/mL,空气=1):未确定

4.       熔点(ºC):>300

5.       沸点(ºC,常压):未确定

6.       沸点(ºC0.6mmHg):未确定

7.       折射率:未确定

8.       闪点ºF):未确定

9.       比旋光度º):未确定

10.    自燃点或引燃温度(ºC):未确定

11.    蒸气压(20ºC):未确定

12.    饱和蒸气压(kPa,60ºC):未确定

13.    燃烧热(KJ/mol):未确定

14.    临界温度(ºC):未确定

15.    临界压力(KPa):未确定

16.    油水(辛醇/水)分配系数的对数值:未确定

17.    爆炸上限(%,V/V):未确定

18.    爆炸下限(%,V/V):未确定

19.    溶解性:溶于水,0.1g/mL

安全信息展开↓

WGK_Germany:
3
德国有关水污染物质的分类清单
安全说明:
S22-S24/25
安全标志:
S22:不要吸入粉尘。
S24/25:防止皮肤和眼睛接触。

毒理性展开↓

毒理学数据:

主要的刺激性影响:

在皮肤上面:刺激皮肤和粘膜

在眼睛上面:刺激的影响

致敏作用:没有已知的敏化现象

生态数据:

对水少是稍微危害的,不要让未稀释或大量的产品接触地下水、水道或污水系统

若无政府许可,勿将材料排入周围环境.

MSDS 展开↓

Name: Riboflavin 5'-Phosphate Sodium Salt, Dihydrate, 73.0-79.0% (on Dry Material Safety Data Sheet
Synonym: None.
CAS: 6184-17-4
Section 1 - Chemical Product MSDS Name: Riboflavin 5'-Phosphate Sodium Salt, Dihydrate, 73.0-79.0% (on Dry Material Safety Data Sheet
Synonym: None.
SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
6184-17-4 Riboflavin 5'-Phosphate Sodium Salt, D 73-79 unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.
SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW The toxicological properties of this material have not been fully investigated. Potential Health Effects
Eye:
May cause eye irritation. The toxicological properties of this material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.
SECTION 4 - FIRST AID MEASURES
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:


SECTION 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.
SECTION 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.)
SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 6184-17-4: Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C17H20N4NaO9P.2H2O
Molecular Weight: 514.35
SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide, sodium oxide.
Hazardous Polymerization: Has not been reported
SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 6184-17-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Riboflavin 5'-Phosphate Sodium Salt, Dihydrate - Not listed by ACGIH, IARC, or NTP.
SECTION 12 - ECOLOGICAL INFORMATION
SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations.
SECTION 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:


SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 6184-17-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 6184-17-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 6184-17-4 is not on the TSCA Inventory because it is a hydrate. It is considered to be listed if the CAS number for the anhydrous form is on the inventory (40CFR720.3(u)(2)).
SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 2/05/1999 Revision #2 Date: 3/18/2003 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.

SECTION 16 - ADDITIONAL INFORMATION
N/A

分子结构与计算化学数据展开↓

分子结构数据


 

计算化学数据


1、   疏水参数计算参考值(XlogP):-2.6

2、   氢键供体数量:5

3、   氢键受体数量:10

4、   可旋转化学键数量:6

5、   互变异构体数量:15

6、   拓扑分子极性表面积(TPSA):208

7、   重原子数量:31

8、   表面电荷:-1

9、   复杂度:725

10、   同位素原子数量:0

11、   确定原子立构中心数量: 3

12、   不确定原子立构中心数量:0

13、   确定化学键立构中心数量:0

14、   不确定化学键立构中心数量:0

15、   共价键单元数量:1

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