柠檬酸铁铵

柠檬酸铁铵 基本信息
CAS号 1185-57-5 分子式 C6H8FeNO7
分子量 261.97500 精确质量  261.96500
PSA  102.37000 LogP  -1.15840

基本信息 展开↓

CAS号:
1185-57-5
分子式:
C6H8FeNO7
分子量:
261.97500
中文名称:
柠檬酸铁铵
英文名称:
Ammonium ferric citrate
中文别名:
柠檬酸铁铵;
柠檬酸铁(III)铵;
枸橼酸铁铵;
2-羟基-1,2,3-丙三羧酸铁(III)铵盐;
柠檬酸铁胺
英文别名:
Ammonium ferric citrate;
Ammonium iron(III) citrate;
Ammonium Ferric Citrate;
Citric acid iron ammonium;
Ironandammoniumcit-rate;
Amonium Iron(III) Citrate Supplement;
IRON AMMONIUM CITRATE;
Ammoniumironcitrate;
AmmoniumFerricCitrateUsp;
Ferricammoniumcitrae;
Ferric
精确分子量/精确质量:
261.96500
极性分子表面积/PSA:
102.37000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
贝尔斯坦号/MDL:
MFCD00013099
EINECS:
214-686-6
PubChem:
24902112
InChI:
InChI=1/C7H10O7.Fe.H3N/c8-4(9)1-7(14,2-5(10)11)3-6(12)13;;/h14H,1-3H2,(H,8,9)(H,10,11)(H,12,13);;1H3

生产制备方法及用途展开↓

制备方法


1.在硫酸铁溶液中加入氨水,生成氢氧化铁沉淀;过滤、水洗至无硫酸反应,然后加入柠檬酸,并加热至60℃,使沉淀全部溶解;再用氨水中和,浓缩至糖浆状,并涂布于玻璃板上,经微温干燥后剥离得小片状成品。 Fe2(SO4)3+6NH3+6H2O→3(NH4)2SO4+2Fe(OH)3↓ 2C6H8O7+3NH4OH+Fe(OH)3→(C6H5O7)2Fe(NH4)3+6H2O 也可以硫酸亚铁为原料,将28g FeSO4·7H2O溶于4rnL水中,加入98%的浓硫酸3 rnL,再滴加5mL 36%的双氧水,升温至83℃,搅拌0.5h,用铁氰化钾检验显蓝色为反应终点;然后加入100mL蒸馏水,在80℃下搅拌加入40%的NaOH,使溶液呈碱性,将沉淀抽滤,用热水洗至无硫酸根为止。将制得的Fe(OH)3加入溶有14g柠檬酸的100mL水的溶液,在95℃下恒温搅拌1h;然后冷却至50℃,再加入适量的氨水,冷却至室温,静置澄清,上层清液蒸发浓缩至膏状,在60~80℃下烘干即得产品,收率91%。 2.在由硫酸亚铁和氨水制造的氢氧化铁中添加适量的柠檬酸溶液,将其浓缩所得的浆料涂敷于玻璃板干燥后,从玻璃板上剥离而制得。 3.将氢氧化铁溶于柠檬酸,用氨水中和,于60℃以下蒸发而得.

合成制备方法


1.在硫酸铁溶液中加入氨水,生成氢氧化铁沉淀;过滤、水洗至无硫酸反应,然后加入柠檬酸,并加热至60℃,使沉淀全部溶解;再用氨水中和,浓缩至糖浆状,并涂布于玻璃板上,经微温干燥后剥离得小片状成品。
Fe2(SO4)3+6NH3+6H2O→3(NH4)2SO4+2Fe(OH)3↓
2C6H8O7+3NH4OH+Fe(OH)3→(C6H5O7)2Fe(NH4)3+6H2O
也可以硫酸亚铁为原料,将28g FeSO4·7H2O溶于4rnL水中,加入98%的浓硫酸3 rnL,再滴加5mL 36%的双氧水,升温至83℃,搅拌0.5h,用铁氰化钾检验显蓝色为反应终点;然后加入100mL蒸馏水,在80℃下搅拌加入40%的NaOH,使溶液呈碱性,将沉淀抽滤,用热水洗至无硫酸根为止。将制得的Fe(OH)3加入溶有14g柠檬酸的100mL水的溶液,在95℃下恒温搅拌1h;然后冷却至50℃,再加入适量的氨水,冷却至室温,静置澄清,上层清液蒸发浓缩至膏状,在60~80℃下烘干即得产品,收率91%。

2.在由硫酸亚铁和氨水制造的氢氧化铁中添加适量的柠檬酸溶液,将其浓缩所得的浆料涂敷于玻璃板干燥后,从玻璃板上剥离而制得。

3.将氢氧化铁溶于柠檬酸,用氨水中和,于60℃以下蒸发而得.

用途简介


1.柠檬酸铁铵作为食品铁强化剂,吸收效果比无机铁好。我国规定可用于食盐和夹心糖,使用量为4000~8000mg/kg;在高铁谷物及其制品(每日限制这类食品50g)中为1200~1350mg/kg;在乳制品和婴幼儿食品中为400~800mg/kg;在谷类及其制品中为160~330mg/kg;在饮料中为70~140mg/kg。 2.本品可作为铁质强化剂、抗贫血用铁剂,亦可用作食盐的抗结块剂;还可作食品、饲料添加剂的抗结块剂。

用途


1.柠檬酸铁铵作为食品铁强化剂,吸收效果比无机铁好。我国规定可用于食盐和夹心糖,使用量为4000~8000mg/kg;在高铁谷物及其制品(每日限制这类食品50g)中为1200~1350mg/kg;在乳制品和婴幼儿食品中为400~800mg/kg;在谷类及其制品中为160~330mg/kg;在饮料中为70~140mg/kg。

2.本品可作为铁质强化剂、抗贫血用铁剂,亦可用作食盐的抗结块剂;还可作食品、饲料添加剂的抗结块剂。

物化性质展开↓

外观与性状:
淡黄色棕色至红色固体,带有一种微弱氨气味
密度:
1.8 g/cm3 (20ºC)
沸点:
197ºC
水溶解性:
1200 g/L (20 ºC)
存储条件/存储方法:
库房低温,通风,干燥
稳定性相关:

如果遵照规格使用和储存则不会分解,未有已知危险反应,避免氧化物

本品是由铁、铵和柠檬酸组成的结构不明的络盐。应制造条件不同,具有多种组成。棕色、绿色或酱红色透明薄片或颗粒,或棕黄色粉末。无臭或稍带氨臭和温和的铁金属味。空气中易潮解,易生霉。极易溶于水(1g/0.5mL),水溶液近中性,不溶于乙醇和乙醚。5%的水溶液pH值约为5.0~8.0。  

其它信息:

1.       性状:红棕色颗粒或石榴红透明鳞片或棕黄色粉末。无气味或微有氨臭。有碱铁味。

2.       密度(g/mL,25/4℃): 未确定

3.       相对蒸汽密度(g/mL,空气=1):未确定

4.       熔点(ºC):未确定

5.       沸点(ºC,常压):未确定

6.       沸点(ºC,5.2kPa):未确定

7.       折射率:未确定

8.       闪点(ºC):未确定

9.       比旋光度(º):未确定

10.    自燃点或引燃温度(ºC):未确定

11.    蒸气压(kPa,25ºC):未确定

12.    饱和蒸气压(kPa,60ºC):未确定

13.    燃烧热(KJ/mol):未确定

14.    临界温度(ºC):未确定

15.    临界压力(KPa):未确定

16.    油水(辛醇/水)分配系数的对数值:未确定

17.    爆炸上限(%,V/V):未确定

18.    爆炸下限(%,V/V):未确定

19.    溶解性:极易潮解,露光还原为亚铁盐。易溶于水,几乎不溶于乙醇。

安全信息展开↓

海关代码:
2918150000
WGK_Germany:
3
德国有关水污染物质的分类清单
危险类别码:
R36/37/38
安全说明:
S26-S36
RTECS号:
GE7540000
危险标志:
Xi:Irritant

化学图谱

  1. 柠檬酸铁铵红外图谱(IR1)

  2. 柠檬酸铁铵红外图谱(IR2)

上一页 1/4 下一页

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GE7540000
CHEMICAL NAME :
Citric acid, ammonium iron(3+) salt
CAS REGISTRY NUMBER :
1185-57-5
LAST UPDATED :
199712
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C6-H8-O7.xFe.xH4-N
生态数据:

对水是稍微有危害的不要让未稀释或大量的产品接触地下水、水道或者污水系统,若无政府许可,勿将材料排入周围环境

MSDS 展开↓

Name: Ammonium Iron(III)-Citrate Material Safety Data Sheet
Synonym: Ferric Ammonium Citrate, Citric Acid Ammonium Iron (3+) Salt
CAS: 1185-57-5
Section 1 - Chemical Product   MSDS Name:Ammonium Iron(III)-Citrate Material Safety Data Sheet
Synonym:Ferric Ammonium Citrate, Citric Acid Ammonium Iron (3+) Salt

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
1185-57-5 FERRIC AMMONIUM CITRATE 100 214-686-6
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause irritation, pain, blurred vision, and possible burns.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. Inorganic iron compounds may cause gastrointestinal irritation and damage, vomiting, pulmonary edema, convulsions, rapid heart beat and low blood pressure. Ingestion of iron compounds may cause hemorrhage and necrosis of the stomach with shock, severe diarrhea, and possible coma.
Inhalation:
May cause respiratory tract irritation.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Antidote: The use of Deferoxamine as a chelating agent should be determined only by qualified medical personnel.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Do not store in direct sunlight. Keep containers tightly closed.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Solid
Appearance: yellow to green
Odor: None reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Decomposes.
Freezing/Melting Point: Decomposes.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Soluble.
Specific Gravity/Density: 1.8 @ 20C
Molecular Formula: Mixture
Molecular Weight: 0

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, light, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents - light.
Hazardous Decomposition Products:
Ammonia.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 1185-57-5: GE7540000 LD50/LC50:
Not available.
Carcinogenicity:
FERRIC AMMONIUM CITRATE - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Other No information available.

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 1185-57-5: No information available.
United Kingdom Occupational Exposure Limits
Canada
CAS# 1185-57-5 is listed on Canada's DSL List.
CAS# 1185-57-5 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 1185-57-5: OEL-DENMARK:TWA 1 mg(Fe)/m3 JANUARY 1993
OEL-FINLAND:TWA 1 mg(Fe)/m3 JANUARY 1993
OEL-THE NETHERLANDS:TWA 1 mg(Fe)/m3 JANUARY 1993
OEL-SWITZERLAND:TWA 1 mg(Fe)/m3 JANUARY 1993
OEL-UNITED KINGDOM:TWA 1 mg(Fe)/m3;STEL 2 mg(Fe)/m3 JANUARY 1993
US FEDERAL
TSCA
CAS# 1185-57-5 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

海关数据查看详细

中国海关编码:2918150000

概述:
2918150000. 柠檬酸盐和柠檬酸酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:4ABxy(出口许可证,入境货物通关单,出境货物通关单出口许可证(加工贸易),出口许可证(边境小额贸易)). 最惠国关税:6.5%. 普通关税:30.0%
申报要素:
品名, 成分含量, 用途
监管条件:
4.出口许可证A.入境货物通关单B.出境货物通关单x.出口许可证(加工贸易)y.出口许可证(边境小额贸易)
检验检疫:
R.进口食品卫生监督检验S.出口食品卫生监督检验N.出口商品检验
摘要/Summary:
2918150000. other salts and esters of citric acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:4ABXY(export license,certificate of inspection for goods inward,certificate of inspection for goods outwardexport license(processing trade),export license(border small volume trade)). MFN tariff:6.5%. General tariff:30.0%

分子结构与计算化学数据展开↓

分子结构数据


1、摩尔折射率:无可用的

2、摩尔体积(cm3/mol):无可用的

3、等张比容(90.2K):无可用的

4、表面张力(dyne/cm):无可用的

5、介电常数:无可用的

6、极化率(10-24cm3):无可用的

7、单一同位素质量:261.965019 Da

8、标称质量:262 Da

9、平均质量:261.9752 Da

计算化学数据


1、   氢键供体数量:2

2、   氢键受体数量:8

3、   可旋转化学键数量:2

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