CHEMICAL IDENTIFICATION

RTECS NUMBER :

DR9840000

CHEMICAL NAME :

Berbine, 2,3,9,10-tetramethoxy-, hydrochloride, (+-)-

CAS REGISTRY NUMBER :

6024-85-7

LAST UPDATED :

199012

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C21-H25-N-O4.Cl-H

MOLECULAR WEIGHT :

391.93

WISWESSER LINE NOTATION :

T D6 B666 KN&TT&J GO1 HO1 PO1 QO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1160 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 17,30,1983

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

121500 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 5,163,1946