CHEMICAL IDENTIFICATION

RTECS NUMBER :

GB6240000

CHEMICAL NAME :

Chromium hydroxide sulfate

CAS REGISTRY NUMBER :

12336-95-7

LAST UPDATED :

199709

DATA ITEMS CITED :

13

MOLECULAR FORMULA :

Cr-H-O5-S

MOLECULAR WEIGHT :

165.07

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - woman

DOSE/DURATION :

960 mg/kg

TOXIC EFFECTS :

Cardiac - other changes Gastrointestinal - changes in structure or function of endocrine pancreas Gastrointestinal - necrotic changes

MUTATION DATA

TYPE OF TEST :

Sister chromatid exchange

TEST SYSTEM :

Rodent - hamster Ovary

DOSE/DURATION :

10 mg/L

REFERENCE :

CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 6,1327,1985 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0022 No. of Facilities: 51 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 1155 (estimated) No. of Female Employees: 51 (estimated)

毒理学数据：

口服- 大鼠  LD50 7760 毫克/ 公斤; 口服- 小鼠 LD50:2900 毫克/公斤