CHEMICAL IDENTIFICATION

RTECS NUMBER :

YM6105000

CHEMICAL NAME :

1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, (+-)-tropate (ester), 8-oxide

CAS REGISTRY NUMBER :

4438-22-6

LAST UPDATED :

198708

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C17-H23-N-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

RDMU** "Vergleichende Untersuchungen uber Genatropin und Atropin, Dissertation," Rathscheck, U., Pharmakologischen Institut der Westfalichen Wilhelms-Universitat Muenster/Westf., Fed. Rep. Ger., 1934 Volume(issue)/page/year: -,-,1934

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

225 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,513,1948