CHEMICAL IDENTIFICATION

RTECS NUMBER :

DT4750000

CHEMICAL NAME :

Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-phenyl-, 3-(diethylamino)propyl ester

CAS REGISTRY NUMBER :

20448-86-6

LAST UPDATED :

199203

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C21-H31-N-O2

MOLECULAR WEIGHT :

329.53

WISWESSER LINE NOTATION :

L55 ATJ CVO3N2&2 CR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

112 mg/kg

TOXIC EFFECTS :

Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

26 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960