CHEMICAL IDENTIFICATION

RTECS NUMBER :

QD0877000

CHEMICAL NAME :

Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-

CAS REGISTRY NUMBER :

467-15-2

LAST UPDATED :

198612

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C17-H19-N-O3

MOLECULAR WEIGHT :

285.37

WISWESSER LINE NOTATION :

T B6566 B5/CO 4ABBC Q BX HO PM GHT&&TTJ FQ JO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

365 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :

JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 112,191,1954

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

600 mg/kg

TOXIC EFFECTS :

Behavioral - analgesia Lungs, Thorax, or Respiration - other changes

REFERENCE :

CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 19,1,1971