| [(3aS,4R,6R)-4-(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxy-tert-butyl-dimethylsilane 基本信息 | |||
|---|---|---|---|
| CAS号 | 115479-39-5 | 分子式 | C20H30ClN3O4Si |
| 分子量 | 440.00800 | 精确质量 | 439.16900 |
| PSA | N/A | LogP | N/A |
合成路线 共1页 102690-94-8
102690-94-8
+
3680-69-1
4-氯吡咯并嘧啶
→
~66%
115479-39-5
[(3aS,4R,6R)-4-(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxy-tert-butyl-dimethylsilane
102690-94-8
102690-94-8
+
3680-69-1
4-氯吡咯并嘧啶
→
115479-39-5
[(3aS,4R,6R)-4-(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxy-tert-butyl-dimethylsilane
+
120401-30-1
4-chloro-7-[5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-α-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine
75921-20-9
5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β-D-ribofuranose
→
115479-39-5
[(3aS,4R,6R)-4-(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxy-tert-butyl-dimethylsilane
3680-69-1
4-氯吡咯并嘧啶
+
1000982-02-4
5-O-tert-butyldimethylsilyl-5-deoxy-2,3-O-isopropylidene-α/β-D-ribofuranosyl chloride
→
115479-39-5
[(3aS,4R,6R)-4-(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxy-tert-butyl-dimethylsilane
+
120401-30-1
4-chloro-7-[5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-α-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine