二甲基硅油350

二甲基硅油350 基本信息
CAS号 8050-81-5 分子式 C6H18O4Si3
分子量 238.46100 精确质量  238.05100
PSA  52.60000 LogP  1.56770

基本信息 展开↓

CAS号:
8050-81-5
分子式:
C6H18O4Si3
分子量:
238.46100
中文名称:
二甲基硅油350
英文名称:
POLYDIMETHYLSILOXANE
中文别名:
二甲基硅油350;
甲基硅油;
二甲基聚硅氧烷;
二甲基硅油 350;
二甲基硅油(1);
硅酮DC-200;
甲基硅氧烷;
聚硅氧烷DC-200;
硅酮 DC-200
英文别名:
POLYDIMETHYLSILOXANE;
4-trimethylsilylstyrene;
poly(3-hexylthiophene);
poly(4-trimethylsilylstyrene);
Simethicone;
p-(Trimethylsilyl)styrene;
trimethyl-(4-vinyl-phenyl)-silane;
3-(Hex-1-yl)thiophene;
poly(acrylamide);
3-hexyltiophene
精确分子量/精确质量:
238.05100
极性分子表面积/PSA:
52.60000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。

生产制备方法及用途展开↓

制备方法


作被膜剂,我国规定可用于蔬、果的保鲜,最大使用量为0.0009g/kg。

合成制备方法


采用碱法和酸法。碱法是以二甲基环硅氧烷为原料,在六甲基二硅醚止链剂和四甲基氢氧化铵催化剂存在下,进行调聚反应而得。酸法是以硅橡胶的低沸物为原料,在六甲基二硅醚止链剂和浓硫酸催化剂存在下,进行调聚反应,然后经除酸、洗涤、脱色、抽滤而得。

用途简介


用途


广泛用于护肤霜、护手霜、皮肤清洁剂、防晒用品、剃须膏、除臭剂、浴液、护发素等化妆品中。还可制造擦亮剂,也用作消泡剂。对多种维生素、激素、杀菌剂、抗炎药剂均有溶解能力,与化妆品的各种成分相溶性好,并可在皮肤表面形成薄层,有疏水性,可使维生素和药物在皮肤表面保持较长时间,有稳定的营养效果,也可使头发柔软、滑爽,改善梳理并增加光泽。

物化性质展开↓

密度:
1 g/mL at 20ºC
沸点:
96.5ºC at 760 mmHg
闪点:
6.3ºC
折射率:
n20/D 1.406
稳定性相关:

        硅油具有生理惰性,无臭、无味、无毒、无刺激,对皮肤不过敏。硅油能在皮肤表面形成均匀的防水、透气的保护膜,并能防止紫外线对皮肤的侵害。与皮肤的相容性好,与化妆品中其他组分有良好的配伍性能。乳化性好,并具有抗静电性。

其它信息:

1.性状:无色透明液体或为黏性液体,几乎无气味。

2.相对密度:0.850~1.050。

3.折射率:1.385~1.410。

4.溶解度:不溶于水和乙醇、四氯化碳、苯、氯仿、乙醚、甲苯及其他有机溶剂。

安全信息展开↓

危险类别码:
36/37-20
安全说明:
26-36-23
危险标志:
Xn: Harmful;Xi: Irritant;

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VW6200000
CHEMICAL NAME :
Simethicone
CAS REGISTRY NUMBER :
8050-81-5
LAST UPDATED :
199504

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
AMSGAO AMA Archives of Surgery. (Chicago, IL) V.61-80, 1950-60. For publisher information, see ARSUAX. Volume(issue)/page/year: 78,220,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes
REFERENCE :
AMSGAO AMA Archives of Surgery. (Chicago, IL) V.61-80, 1950-60. For publisher information, see ARSUAX. Volume(issue)/page/year: 78,220,1959 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4515 No. of Facilities: 1163 (estimated) No. of Industries: 6 No. of Occupations: 20 No. of Employees: 90654 (estimated) No. of Female Employees: 75193 (estimated)

MSDS 展开↓


Section 1. Chemical Product and Company Identification
    Simethicone
    Common Name/
    Trade Name
    Manufacturer
    Commercial Name(s)
    Synonym
    Chemical Name
    Chemical Family
    Simethicone

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at    
    least 15 minutes. Get medical attention if irritation occurs.
    Skin Contact        Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.    
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an    
    unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
    clothing such as a collar, tie, belt or waistband.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        CLOSED CUP: 196°C (384.8°F).    
    Flammable Limits        Not available.    
    Products of Combustion        Not available.    
    Fire Hazards in Presence of Slightly flammable to flammable in presence of open flames and sparks, of heat.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    Risks of explosion of the product in presence of static discharge: Not available.
    of Various Substances
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Not available.
    Special Remarks on
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards

Section 6. Accidental Release Measures
    Small Spill        Absorb with an inert material and put the spilled material in an appropriate waste disposal.    
    Large Spill        Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by    
    spreading water on the contaminated surface and allow to evacuate through the sanitary system.
    Simethicone

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not    
    breathe gas/fumes/ vapor/spray. Keep away from incompatibles such as oxidizing agents.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area.    

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their    
    respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the
    work-station location.
    Personal Protection
    Safety glasses. Lab coat.
    Personal Protection in Case of Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a
    a Large Spill        specialist BEFORE handling this product.    
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Liquid. (viscous, translucent, oil-like)        Bland. Mild.    
    Odor
    Taste        Not available.    
    Molecular Weight        Not available.    
    Color        Light Gray or white    
    pH (1% soln/water)        Not applicable.    
    Boiling Point        >150°C (302°F)    
    Melting Point        <-50°C (-58°F)    
    Critical Temperature        Not available.    
    0.995 @ 25 C.(Water = 1) (from Vendor MSDS)
    Specific Gravity
    0.980 (Aldrich; Handbook of Fine Chemicals and Laboratory Equipment, 2000-2001)
    <0.1 kPa (@ 20°C)
    Vapor Pressure
    Vapor Density        >1 (Air = 1)    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Not available.
    Ionicity (in Water)
    Dispersion Properties        Not available.    
    Solubility        Insoluble in cold water, hot water.    
    Insoluble in alcohol.

Section 10. Stability and Reactivity Data
    Stability        The product is stable.    
    Not available.
    Instability Temperature
    Conditions of Instability        Heat, incompatible materials    
    Incompatibility with various        Reactive with oxidizing agents.    
    substances
    Corrosivity        Not available.    
    Simethicone
    Not available.
    Special Remarks on
    Reactivity
    Not available.
    Special Remarks on
    Corrosivity
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Skin. Eye contact.    
    Toxicity to Animals        LD50: Not available.    
    LC50: Not available.
    Chronic Effects on Humans May cause damage to the following organs: skin, eyes.
    Other Toxic Effects on
    Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
    Humans
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        Not available.    
    Chronic Effects on Humans
    Special Remarks on other        Acute Potential Health Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation. No evidence of harmful effects from available information    
    Eyes: May cause eye irritation. No evidence of harmful effects from available information.
    Inhalation: Low hazard. Short-term harmful effects are not expected from vapor generated at ambient
    temperature.
    Ingestion: Low hazard. It is not absorbed from the gastrointestinal tract. It is not expected to have any major
    toxic effects. It may cause stomach upset, bloating, constipatioin, diarrhea, gas, heartburn. No evidence of
    harmful effects from availble information.

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products may    
    arise.
    Toxicity of the Products        Not available.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Not applicable.
    Identification
    Not applicable.
    Special Provisions for
    Transport
    Simethicone
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    Regulations
    California        California prop. 65: This product contains the following ingredients for which the State of California has found    
    to cause cancer which would require a warning under the statute: No products were found.
    Proposition 65
    Warnings
    California prop. 65: This product contains the following ingredients for which the State of California has found
    to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).    
    WHMIS (Canada) Not controlled under WHMIS (Canada).
    Other Classifications
    DSCL (EEC)        This product is not classified according Not applicable.    
    to the EU regulations.
    Health Hazard
    HMIS (U.S.A.)        1 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    1 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    a
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Not applicable.
    Lab coat.
    Not applicable.
    Safety glasses.


SECTION 16 - ADDITIONAL INFORMATION
N/A
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