5-(difluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

5-(difluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione 基本信息
CAS号 101527-46-2 分子式 C10H12F2N2O5
分子量 278.20900 精确质量  278.07100
PSA  104.81000 LogP  -0.47280

基本信息 展开↓

CAS号:
101527-46-2
3D弹球模型:
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分子式:
C10H12F2N2O5
分子量:
278.20900
英文名称:
5-(difluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
英文别名:
5-(difluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;
5-Difluoromethyl-2'-deoxyuridine;
Thymidine,a,a-difluoro-(9CI);
2'-Deoxy-5-difluoromethyluridine;
F2-Tdr
精确分子量/精确质量:
278.07100
极性分子表面积/PSA:
104.81000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
InChI:
The Key: YATQDPXPMDMPID-RRKCRQDMSA-N

物化性质展开↓

密度:
1.573g/cm3
折射率:
1.546

合成路线查看所有的合成路线

  • 118070-23-8

    3',5'-di-O-(tert-butyldiphenyl)silyl-α,α-difluorothymidine

  • ~57%

  • 101527-46-2

    5-(difluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

  • 101527-40-6

    5'-O-TBDPS-dT

  • 101527-46-2

    5-(difluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

  • 118070-22-7

    3',5'-bis-O-(tert-butyldiphenylsilyl)-5-bromomethyl-2'-deoxyuridine

  • 101527-46-2

    5-(difluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

上下游相关产品

上游产品

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  • 118070-23-8

    3',5'-di-O-(tert-butyldiphenyl)silyl-α,α-difluorothymidine

  • 50-89-5

    胸苷

  • 118068-35-2

    3',5'-bis-O-(tert-butyldiphenylsilyl)-thymidine

  • 118068-37-4

    3',5'-di-O-(tert-butyldiphenyl)silyl-2'-deoxy-5-formyluridine

  • 118068-36-3

    3',5'-di-O-(tert-butyldiphenyl)silyl-α-hydroxythymidine

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