CHEMICAL IDENTIFICATION

RTECS NUMBER :

CP0350000

CHEMICAL NAME :

Bacitracin A

CAS REGISTRY NUMBER :

22601-59-8

LAST UPDATED :

199512

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C66-H103-N17-O16-S

MOLECULAR WEIGHT :

1422.92

WISWESSER LINE NOTATION :

T5N CS AUTJ BYZY2 EVMY1Y&&VMY2VQVMYY2&&VM-WT-23-VM DVM GVM JVM MVM QVMTJ C3Z FY2 I1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

158 mg/kg

TOXIC EFFECTS :

Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity)

REFERENCE :

BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,417,1951 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

474 mg/kg/3D-I

TOXIC EFFECTS :

Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :

BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,417,1951