阿扎司特

阿扎司特 基本信息
CAS号 114607-46-4 分子式 C9H7N5O3
分子量 233.18400 精确质量 　233.05500
PSA 　120.86000 LogP 　-0.03720
我要卖该产品 我要采购该产品
充值推广 查看更多供应商
目录
基本信息 物化性质 毒性

基本信息 展开↓

CAS号：
114607-46-4
3D弹球模型：
立即前往扯扯看
分子式：
C9H7N5O3
分子量：
233.18400
中文名称：
阿扎司特
英文名称：
2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid
中文别名：
阿扎司特
英文别名：
2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid;
WP-871;
Acitazanolast,WP-871;
MTCC;
Acitazanolast
精确分子量/精确质量：
233.05500
极性分子表面积/PSA：
120.86000
油水分配系数/LogP：

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值，反映了物质在油水两相中的分配情况。其中、LogP值越大，说明该物质越亲油；反之，LogP值越小，则说明该物质越亲水。
InChI：
The Key: VWQZJJZGISNFOE-UHFFFAOYSA-N

物化性质展开↓

密度：
1.66g/cm3
折射率：
1.718

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AJ1476901
CHEMICAL NAME :
Acetic acid, oxo-((3-(1H-tetrazol-5-yl)phenyl)amino)-
CAS REGISTRY NUMBER :
114607-46-4
LAST UPDATED :
199512
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C9-H7-N5-O3
MOLECULAR WEIGHT :
233.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 49,111,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1927 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression Blood - normocytic anemia
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 49,111,1995
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1500 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Cardiac - arrhythmias (including changes in conduction) Gastrointestinal - nausea or vomiting
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 49,231,1995 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
22680 mg/kg/28D-C
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in platelet count Related to Chronic Data - death
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,107,1989
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
28 gm/kg/4W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - other changes in urine composition Blood - normocytic anemia
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 49,235,1995
立即下载安装“化学加”APP
专业、功能强大，随时调用更加方便
下载APP