二盐酸珠氯噻醇

二盐酸珠氯噻醇 基本信息
CAS号 633-59-0 分子式 C22H26Cl2N2OS
分子量 437.42600 精确质量 　436.11400
PSA 　52.01000 LogP 　4.91410
我要卖该产品 我要采购该产品
充值推广 查看更多供应商
目录
基本信息 毒性

基本信息 展开↓

CAS号：
633-59-0
分子式：
C22H26Cl2N2OS
分子量：
437.42600
中文名称：
二盐酸珠氯噻醇
英文名称：
1-Piperazineethanol,4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, hydrochloride (1:2)
中文别名：
二盐酸珠氯噻醇;
珠氯噻醇盐酸盐;
高抗素;
(3beta)-cholest-5-en-3-yl propanoate;
Cholesteryl propionate;
[4-[(4-diethylaminophenyl)-phenyl-methylene]-1-cyclohexa-2,5-dienylidene]-diethyl-ammonium,sulfuric acid;
Brilliant green;
Basic Viloet14;
Fuchsin basic;
Basic Violet 14;
bromophthal;
Tetrabromophthalic anhydride;
Phosphorsaeure-bis-(p-nitro-phenylester) [German];
p-Nitrophenyl monohydrogen phosphate;
Bis(4-nitrophenyl) hydrogen phosphate;
Phosphoric acid, bis(p-nitrophenyl) ester;
Bis(p-nitrophenyl)phosphate;
Pfizer-E;
Qidmycin;
Stearic acid, compd. with erythromycin (1:1);
UNII-LXW024X05M;
Wyamycin S;
Erythromycin octadecanoate (salt);
Erythromycin, stearate (salt);
octadecanoic acid - (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9;
(2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-me
英文别名：
1-Piperazineethanol,4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, hydrochloride (1:2);
CLOPENTHIXOL DIHYDROCHLORIDE;
2-(4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethanol dihydrochloride;
2-[4-[3-(2-Chlorothioxanthen-9-Ylidene)Propyl]Piperazin-1-Yl]Ethanol Dihydrochloride;
4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]piperazine-1-ethanol dihydrochloride
精确分子量/精确质量：
436.11400
极性分子表面积/PSA：
52.01000
油水分配系数/LogP：

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值，反映了物质在油水两相中的分配情况。其中、LogP值越大，说明该物质越亲油；反之，LogP值越小，则说明该物质越亲水。
EINECS：
211-194-3
InChI：
InChI=1/C22H25ClN2OS.2ClH/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26;;/h1-2,4-8,16,26H,3,9-15H2;2*1H

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL8575000
CHEMICAL NAME :
1-Piperazineethanol, 4-(3-(2-chlorothioxanthen-9-ylidene)propyl)-, dihydrochloride
CAS REGISTRY NUMBER :
633-59-0
LAST UPDATED :
199507
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C22-H25-Cl-N2-O-S.2Cl-H
MOLECULAR WEIGHT :
473.92
WISWESSER LINE NOTATION :
T C666 BS IYJ EG IU3- AT6N DNTJ D2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
105 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
560 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
222 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
111 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3996211
立即下载安装“化学加”APP
专业、功能强大，随时调用更加方便
下载APP