CHEMICAL IDENTIFICATION

RTECS NUMBER :

AY3050000

CHEMICAL NAME :

Alanine, N-(N-acetyl-3-(p-(bis(2-chloroethyl)amino)phenyl)alan yl)-3-phenyl-, ethyl ester

CAS REGISTRY NUMBER :

10065-57-3

LAST UPDATED :

199512

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C26-H33-Cl2-N3-O4

MOLECULAR WEIGHT :

522.52

WISWESSER LINE NOTATION :

G2N2GR D1YMV1&VMY1R&VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1150 mg/kg/10D-I

TOXIC EFFECTS :

Related to Chronic Data - death

REFERENCE :

FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,472,1970

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

325 mg/kg/10D-I

TOXIC EFFECTS :

Related to Chronic Data - death

REFERENCE :

FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,472,1970

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Rectal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

640 mg/kg/10D-I

TOXIC EFFECTS :

Related to Chronic Data - death

REFERENCE :

FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,472,1970