| 替格瑞洛 基本信息 | |||
|---|---|---|---|
| CAS号 | 274693-27-5 | 分子式 | C23H28F2N6O4S |
| 分子量 | 522.56800 | 精确质量 | 522.18600 |
| PSA | N/A | LogP | N/A |
合成路线 共1页 1354945-69-9
(1S,2S,3R,5S)-3-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1 ,2-diol
+
1444301-72-7
1444301-72-7
→
~93%
274693-27-5
替格瑞洛
274693-26-4
异亚丙基替卡格雷
→
~91%
274693-27-5
替格瑞洛
1383715-61-4
1383715-61-4
→
~89%
274693-27-5
替格瑞洛
1427524-43-3
1427524-43-3
→
~81%
274693-27-5
替格瑞洛
1451195-46-2
1451195-46-2
→
~61%
274693-27-5
替格瑞洛
1402150-11-1
1402150-11-1
→
~56%
274693-27-5
替格瑞洛
1431867-58-1
1431867-58-1
→
274693-27-5
替格瑞洛
1431867-56-9
1431867-56-9
→
274693-27-5
替格瑞洛
1431867-47-8
1431867-47-8
→
274693-27-5
替格瑞洛
1402735-41-4
1402735-41-4
→
274693-27-5
替格瑞洛
1444301-53-4
(3aS,4R,6S,6aR)-N-benzyl-6-((2-tert-butoxy)ethoxy)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-amine
→
274693-27-5
替格瑞洛
1451195-45-1
1451195-45-1
→
274693-27-5
替格瑞洛
1451196-00-1
1451196-00-1
→
274693-27-5
替格瑞洛
1402150-31-5
1402150-31-5
→
274693-27-5
替格瑞洛
1402150-29-1
2-(((3aR,4S,6R,6aS)-6-((6-chloro-5-formamido-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetic acid
→
274693-27-5
替格瑞洛
1402150-27-9
2-((3aS,4R,6S,6aR)-4-amino-tetrahydro-2,2-dimethyl-3aH-cyclopenta[d][1,3]dioxol-6-yloxy)acetic acid
→
274693-27-5
替格瑞洛
1402150-22-4
2-((3aS,4R,6S,6aR)-4-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)tetrahydro-3aH-spiro[cyclopenta[d][1,3]dioxole-2,1'-cyclopentane]-6-yloxy)ethanol
→
274693-27-5
替格瑞洛
1402150-21-3
2-((3aS,4R,6S,6aR)-4-(5-amino-6-chloro-2-(propylthio)-pyrimidin-4-ylamino)tetrahydro-3aH-spiro[cyclopenta[d][1,3]dioxole-2,1'-cyclopentane]-6-yloxy)ethanol
→
274693-27-5
替格瑞洛
1402150-20-2
2-((3aS,4R,6S,6aR)-4-aminotetrahydro-3aH-spiro[cyclopenta[d][1,3]dioxole-2,1'-cyclopentane]-6-yloxy)ethanol oxalic acid salt
→
274693-27-5
替格瑞洛
1402150-18-8
tert-butyl (3aR,4S,6R,6aS)-4-(2-hydroxyethoxy)tetrahydro-3aH-spiro[cyclopenta[d][1,3]dioxole-2,1'-cyclopentane]-6-ylcarbamate
→
274693-27-5
替格瑞洛
1402150-16-6
ethyl 2-(((3aS,4R,6S,6aR)-4-((tert-butoxycarbonyl)amino)tetrahydro-3aH-spiro[cyclopenta[d][1,3]dioxole-2,1'-cyclopentan]-6-yl)oxy)acetate
→
274693-27-5
替格瑞洛
1402150-12-2
1402150-12-2
→
274693-27-5
替格瑞洛
1402150-08-6
methyl 2-((1S,2S,3S,4R)-4-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyloxy)acetate
→
274693-27-5
替格瑞洛
1402150-07-5
methyl 2-((1S,2S,3S,4R)-4-(5-amino-6-chloro-2-(propylthio)-pyrimidin-4-ylamino)-2,3-dihydroxycyclopentyloxy)acetate
→
274693-27-5
替格瑞洛
1402150-06-4
methyl 2-((1S,2S,3S,4R)-4-(6-chloro-5-nitro-2-(propylthio)-pyrimidin-4-ylamino)-2,3-dihydroxycyclopentyloxy)acetate
→
274693-27-5
替格瑞洛
1402150-02-0
ethyl 2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate
→
274693-27-5
替格瑞洛
1402150-01-9
ethyl 2-((3aR,4S,6R,6aS)-6-(7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]-dioxol-4-yloxy)acetate
→
274693-27-5
替格瑞洛
1402150-30-4
2-((3aS,4R,6S,6aR)-4-amino-tetrahydro-2,2-dimethyl-3aH-cyclopenta[d][1,3]dioxol-6-yloxy)ethanol oxalic acid salt
→
274693-27-5
替格瑞洛
51336-95-9
2-氯-1-(3,4-二氟苯基)乙酮
→
274693-27-5
替格瑞洛
532-20-7
D-Lyxofuranose (9CI)
→
274693-27-5
替格瑞洛
1006376-62-0
替卡格雷中间体
→
274693-27-5
替格瑞洛
376608-70-7
trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarbonyl chloride
→
274693-27-5
替格瑞洛
1006376-61-9
(1R,2R)-乙基2-(3,4-二氟苯基)环丙烷羧酸
→
274693-27-5
替格瑞洛
1006376-63-1
(2S)-2-(3,4-Difluorophenyl)oxirane
→
274693-27-5
替格瑞洛
1006376-60-8
(S)-2-氯-1-(3,4-二氟苯基)乙醇
→
274693-27-5
替格瑞洛
376608-73-0
4,6-dichloro-5-((E)-2-(4-methylphenyl)diazenyl)-2-(propylsulfanyl)pyrimidine
→
274693-27-5
替格瑞洛
376608-72-9
4,6-dihydroxy-5-((E)-2-(4-methylphenyl)diazenyl)-2-(propylsulfanyl)pyrimidine
→
274693-27-5
替格瑞洛
1265919-25-2
1265919-25-2
→
274693-27-5
替格瑞洛
1402150-05-3
1402150-05-3
→
274693-27-5
替格瑞洛
1402150-04-2
1402150-04-2
→
274693-27-5
替格瑞洛
1402150-03-1
2-((3aR,4S,6R,6aS)-6-(5-amino-6-chloro-2-(propylthio)-pyrimidin-4-ylamino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)-acetic acid
→
274693-27-5
替格瑞洛
1431867-57-0
1431867-57-0
→
274693-27-5
替格瑞洛
1431867-54-7
1431867-54-7
→
274693-27-5
替格瑞洛
1427523-79-2
1427523-79-2
→
274693-27-5
替格瑞洛
1427523-82-7
BATAME
→
274693-27-5
替格瑞洛
274693-49-1
Deshydroxyethoxy-2,3-O-(dimethylmethylene) Ticagrelor
→
274693-27-5
替格瑞洛
1427523-80-5
1427523-80-5
→
274693-27-5
替格瑞洛
1402150-28-0
N-[4,6-dichloro-2-(propylthio)-5-pyrimidinyl]Formamide
→
274693-27-5
替格瑞洛
1402150-00-8
ethyl 2-((3aR,4S,6R,6aS)-6-(5-amino-6-chloro-2-(propylthio)-pyrimidin-4-ylamino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)-acetate
→
274693-27-5
替格瑞洛
220352-36-3
(1R,2S)-rel-2-(3,4-二氟苯基)环丙基甲酸
→
274693-27-5
替格瑞洛
1431867-43-4
1431867-43-4
→
274693-27-5
替格瑞洛
1431867-42-3
1431867-42-3
→
274693-27-5
替格瑞洛
1431867-41-2
1431867-41-2
→
274693-27-5
替格瑞洛
1431867-39-8
1431867-39-8
→
274693-27-5
替格瑞洛
1402149-99-8
ethyl 2-((3aR,4S,6R,6aS)-6-(6-chloro-5-nitro-2-(propylthio)-pyrimidin-4-ylamino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)-acetate
→
274693-27-5
替格瑞洛
10257-32-6
(3R,4R,5R)-oxane-2,3,4,5-tetrol
→
274693-27-5
替格瑞洛
78341-96-5
78341-96-5
→
274693-27-5
替格瑞洛
81026-76-8
1-O-methyl-2,3-O-isopropylidene-5-O-(methanesulfonyl)-β-D-ribofuranoside
→
274693-27-5
替格瑞洛
1402149-98-7
Acetic acid, 2-[[(3aR,4S,6R,6aS)-6-aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-, ethyl ester, ethanedioate (1:1)
→
274693-27-5
替格瑞洛
1402149-97-6
ethyl 2-((3aR,4S,6R,6aS)-6-(tert-butoxycarbonylamino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)acetate
→
274693-27-5
替格瑞洛
1444301-62-5
1444301-62-5
→
274693-27-5
替格瑞洛
1402150-32-6
(1S,2S,3R,5S)-3-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)-amino)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
→
274693-27-5
替格瑞洛
1444301-59-0
(1S,2S,3R,5S)-3-(benzylamino)-5-(2-(benzyloxy)ethoxy)cyclopentane-1,2-diol
→
274693-27-5
替格瑞洛
1444301-56-7
tert-butyl ((3aS,4R,6S,6aR)-6-(2-(tert-butoxy)ethoxy)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)carbamate
→
274693-27-5
替格瑞洛
1444301-50-1
1444301-50-1
→
274693-27-5
替格瑞洛
220241-59-8
(3aR,4S,6R,6aS)-6-(6-氯-5-硝基-2-丙硫基-4-吡啶基)氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-醇
→
274693-27-5
替格瑞洛
220241-60-1
(3aR,4S,6R,6aS)-6-(5-胺基-6-氯-2-丙硫基-4-吡啶基)氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-醇
→
274693-27-5
替格瑞洛
1402150-26-8
1402150-26-8
→
274693-27-5
替格瑞洛
1402150-24-6
benzyl (1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)-cyclopentylcarbamate
→
274693-27-5
替格瑞洛
1402150-17-7
1402150-17-7
→
274693-27-5
替格瑞洛
1402150-15-5
1402150-15-5
→
274693-27-5
替格瑞洛
1402150-14-4
benzyl (3aR,4S,6R,6aS)-4-hydroxytetrahydro-3aH-spiro[cyclopenta[d][1,3]dioxole-2,1'-cyclopentane]-6-ylcarbamate
→
274693-27-5
替格瑞洛
1383715-62-5
1383715-62-5
→
274693-27-5
替格瑞洛
50600-40-3
50600-40-3
→
274693-27-5
替格瑞洛
155855-51-9
(3AS,4S,7R,7AS)4,7-亚甲基-4H-1,3-二氧碳基[4,5-D][1,2]恶嗪,四氢-2,2-二甲基-6-(苄基)
→
274693-27-5
替格瑞洛
155934-55-7
D-erythro-Pent-4-enose, 4,5-dideoxy-2,3-O-(1-methylethylidene)- (9CI)
→
274693-27-5
替格瑞洛
4137-56-8
1-甲氧基-2,3-O-异亚丙基-5-O-对甲苯磺酰基-beta-D-呋喃核糖苷
→
274693-27-5
替格瑞洛
4099-85-8
甲基-2,3-O-异亚丙基-beta-D-呋喃核糖苷
→
274693-27-5
替格瑞洛
345898-95-5
N-(((4S,5R)-2,2-dimethyl-5-vinyl-1 ,3-dioxolan-4-yl)methylene)-1-phenylmethanamine oxide
→
274693-27-5
替格瑞洛
1043546-64-0
(2E)-3-(3,4-Difluorophenyl)acryloyl chloride
→
274693-27-5
替格瑞洛
112897-97-9
3,4-二氟肉桂酸
→
274693-27-5
替格瑞洛
155855-53-1
155855-53-1
→
274693-27-5
替格瑞洛
1444301-60-3
(1S,2S,3R,5S)-3-Amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
→
274693-27-5
替格瑞洛
324535-98-0
tert-butyl ((3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-3aH-cyclopenta[d]-[1,3]dioxol-4-yl)carbamate
→
274693-27-5
替格瑞洛
1402150-13-3
1402150-13-3
→
274693-27-5
替格瑞洛
220241-61-2
(3aR,4S,6R,6aS)-6-(7-氯-5-丙硫基-3H-1,2,3-三唑[4,5-d]嘧啶-3-基)四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-醇
→
274693-27-5
替格瑞洛
1383715-60-3
1383715-60-3
→
274693-27-5
替格瑞洛
1383715-59-0
1383715-59-0
→
274693-27-5
替格瑞洛
1383715-57-8
1383715-57-8
→
274693-27-5
替格瑞洛
1383715-56-7
1383715-56-7
→
274693-27-5
替格瑞洛
1383715-55-6
1383715-55-6
→
274693-27-5
替格瑞洛
1345413-22-0
1-(3',4'-difluorophenyl)-3-nitro-propan-1-one
→
274693-27-5
替格瑞洛
1215969-79-1
3-chloro-1-(3',4'-difluorophenyl)-propan-1-one
→
274693-27-5
替格瑞洛
1345413-26-4
trans-(1R,2S)-2-(3,4-difluorophenyl)-1-nitrocyclopropane
→
274693-27-5
替格瑞洛
1345413-25-3
1345413-25-3
→
274693-27-5
替格瑞洛
376608-71-8
(1R,2S)-2-(3,4-二氟苯基)环丙胺 (R)-扁桃酸盐
→
274693-27-5
替格瑞洛
145783-15-9
4,6-二氯-2-丙基硫代嘧啶-5-胺
→
274693-27-5
替格瑞洛
367-11-3
1,2-二氟苯
→
274693-27-5
替格瑞洛
274693-54-8
N-[(3aS,4R,6S,6aR)-四氢-6-(2-羟基乙氧基)-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-基]氨基甲酸苯甲酯
→
274693-27-5
替格瑞洛
274693-53-7
N-[(3aS,4R,6S,6aR)-四氢-6-羟基-2,2-二甲基-4H-环戊烯并-1,3-二氧戊环-4-基]氨基甲酸苄酯
→
274693-27-5
替格瑞洛
1383715-58-9
1383715-58-9
→
274693-27-5
替格瑞洛
1350749-64-2
1350749-64-2
→
274693-27-5
替格瑞洛
145783-12-6
6-羟基-2-(丙基硫代)-4(3h)-嘧啶酮
→
274693-27-5
替格瑞洛
274693-55-9
2-[[(3aR,4S,6R,6aS)-6-氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-基]氧基]乙醇
→
274693-27-5
替格瑞洛
155899-66-4
(3aR,4S,6R,6aS)-6-氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-醇
→
274693-27-5
替格瑞洛
145783-14-8
4,6-二氯-5-硝基-2-丙硫基嘧啶
→
274693-27-5
替格瑞洛
1445580-43-7
(1S,2S,3R,5S)-3-(7-hydroxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
+
1402222-66-5
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride (1:1 )
→
274693-27-5
替格瑞洛
1402150-23-5
1402150-23-5
→
274693-27-5
替格瑞洛
1383715-64-7
1383715-64-7
→
274693-27-5
替格瑞洛
1383715-63-6
1383715-63-6
→
274693-27-5
替格瑞洛