CHEMICAL IDENTIFICATION

RTECS NUMBER :

ON9104700

CHEMICAL NAME :

Malonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3 .2.0)hept-6-yl)-2- phenyl-

CAS REGISTRY NUMBER :

4697-36-3

LAST UPDATED :

199712

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C17-H18-N2-O6-S

MOLECULAR WEIGHT :

378.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2363 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Human Lymphocyte

DOSE/DURATION :

280 mg/L

REFERENCE :

HUTODJ Human Toxicology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants., RG 21 2XS, UK) V.1- 1981- Volume(issue)/page/year: 3,173,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3591 No. of Facilities: 178 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 10079 (estimated) No. of Female Employees: 8399 (estimated)