| 1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione 基本信息 | |||
|---|---|---|---|
| CAS号 | 40733-27-5 | 分子式 | C16H28N2O5Si |
| 分子量 | 356.48900 | 精确质量 | 356.17700 |
| PSA | N/A | LogP | N/A |
合成路线 共1页 913331-03-0
913331-03-0
→
~99%
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
80971-33-1
5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-O-(tert-butyldimethylsilyl)thymidine
→
~94%
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
197719-57-6
197719-57-6
→
~93%
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
226943-40-4
5'-O-tetrahydropyranyl-3'-O-(tert-butyldimethylsilyl)thymidine
→
~93%
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
80971-33-1
5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-O-(tert-butyldimethylsilyl)thymidine
+
18162-48-6
叔丁基二甲基氯硅烷
→
~88%
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
40733-26-4
3,5-双-o-(t-丁基二甲基甲硅烷基)胸腺嘧啶脱氧核苷
→
~87%
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
67-56-1
甲醇
+
80971-33-1
5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-O-(tert-butyldimethylsilyl)thymidine
→
~84%
125016-87-7
1-methoxy-4-[methoxy-(4-methoxyphenyl)-phenylmethyl]benzene
+
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
18162-48-6
叔丁基二甲基氯硅烷
+
40615-39-2
保护胸苷
→
~77%
40615-35-8
bis(4-methoxyphenyl)-phenylmethanol
+
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
912293-98-2
912293-98-2
→
~72%
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
288-32-4
咪唑
+
76-83-5
三苯基氯甲烷
+
18162-48-6
叔丁基二甲基氯硅烷
+
50-89-5
胸苷
→
~68%
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
213552-25-1
5'-O-trityl-3'-O-tert-butyldimethylsilyl thymidine
→
~10%
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
40733-28-6
5’-O-(叔丁基二甲基甲硅烷基)胸苷
→
~5%
65-71-4
5-甲基脲嘧啶
+
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
+
40733-26-4
3,5-双-o-(t-丁基二甲基甲硅烷基)胸腺嘧啶脱氧核苷
+
50-89-5
胸苷
909717-23-3
909717-23-3
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
64722-98-1
1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((4-methoxyphenyl)diphenylmethoxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
250665-56-6
5'-O-[(1H-imidazol-1-yl)carbonyl]-3'-O-(tert-butyldimethylsilyl)thymidine
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
144822-49-1
144822-49-1
+
144822-48-0
1-[5-O-[二(4-甲氧基苯基)苯甲基]-2-脱氧-2-氟-beta-D-阿拉伯呋喃糖基]-5-甲基-2,4(1H,3H)-嘧啶二酮
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
69739-34-0
叔丁基二甲硅基三氟甲磺酸酯
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
35898-26-1
O5'-(4-methyl-benzoyl)-thymidine
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
42926-80-7
1-[(2R,4S,5R)-4-hydroxy-5-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
18162-48-6
叔丁基二甲基氯硅烷
+
50-89-5
胸苷
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
7791-71-1
5’-O-三苯甲基胸苷
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
497-19-8
碳酸钠
+
80971-33-1
5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-O-(tert-butyldimethylsilyl)thymidine
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
18162-48-6
叔丁基二甲基氯硅烷
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
40615-39-2
保护胸苷
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
50-89-5
胸苷
→
40733-27-5
1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione