硫酸莫达林

硫酸莫达林 基本信息
CAS号 2856-75-9 分子式 C10H17N3O4S
分子量 275.32500 精确质量  275.09400
PSA  112.00000 LogP  2.26830

基本信息 展开↓

CAS号:
2856-75-9
分子式:
C10H17N3O4S
分子量:
275.32500
中文名称:
硫酸莫达林
英文名称:
2-methyl-3-piperidin-1-ylpyrazine,sulfuric acid
中文别名:
硫酸莫达林
英文别名:
2-methyl-3-piperidin-1-ylpyrazine,sulfuric acid;
M 7370;
2-Methyl-3-piperidinopyrazine monosulfate;
W3207B;
Pyrazine,2-methyl-3-piperidino-,sulfate;
MODALINE SULFATE
精确分子量/精确质量:
275.09400
极性分子表面积/PSA:
112.00000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。

物化性质展开↓

沸点:
294.2ºC at 760mmHg
闪点:
131.7ºC
蒸汽压:
0.00165mmHg at 25°C

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ3850000
CAS REGISTRY NUMBER :
2856-75-9
LAST UPDATED :
199012
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H15-N3.H2-O4-S
MOLECULAR WEIGHT :
275.36
WISWESSER LINE NOTATION :
T6N DNJ B1 C- AT6KJ &Q &S-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
51 ug/kg
TOXIC EFFECTS :
Behavioral - toxic psychosis Behavioral - changes in motor activity (specific assay)
REFERENCE :
JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 4,86,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
730 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,265,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
190 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,265,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,265,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
275 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,265,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01635
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