CHEMICAL IDENTIFICATION

RTECS NUMBER :

QC7645000

CHEMICAL NAME :

Morphinan, 7,8-didehydro-3,6-alpha-dimethoxy-4,5-alpha-epoxy-17- methyl-

CAS REGISTRY NUMBER :

2859-16-7

LAST UPDATED :

199009

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C19-H23-N-O3

MOLECULAR WEIGHT :

313.43

WISWESSER LINE NOTATION :

T B6566 B6/CO 4ABBC R BX HO PN DU GHT&&TTJ FO1 JO1 P1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

160 mg/kg

TOXIC EFFECTS :

Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)

REFERENCE :

JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 55,127,1935