6-苯氧基-3-吡啶胺

6-苯氧基-3-吡啶胺 基本信息
CAS号 25194-67-6 分子式 C11H10N2O
分子量 186.21000 精确质量  186.07900
PSA  48.14000 LogP  3.03730

基本信息 展开↓

CAS号:
25194-67-6
3D弹球模型:
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分子式:
C11H10N2O
分子量:
186.21000
中文名称:
6-苯氧基-3-吡啶胺
英文名称:
6-phenoxypyridin-3-amine
中文别名:
6-苯氧基-3-吡啶胺
英文别名:
6-phenoxypyridin-3-amine;
5-Amino-2-phenoxypyridine;
6-phenoxypyridin-3-ylamine;
6-Phenoxy-3-Pyridinamine;
3-Amino-6-phenoxypyridine;
6-Phenoxy-3-pyridinamine;
6-phenoxy-3-pyridinylamine;
6-Phenoxypyridine-3-amine;
Pyridine,5-amino-2-phenoxy;
3-Pyridinamine,6-phenoxy;
2-phenoxy-5-amino-pyridine
精确分子量/精确质量:
186.07900
极性分子表面积/PSA:
48.14000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
InChI:
The Key: DETKIRMPBJPJRQ-UHFFFAOYSA-N

物化性质展开↓

密度:
1.197g/cm3
熔点:
71ºC
沸点:
365.3ºC at 760mmHg
闪点:
174.7ºC
折射率:
1.625
蒸汽压:
1.59E-05mmHg at 25°C

安全信息展开↓

海关代码:
2933399090
危险类别码:
R22;R36/37/38
安全说明:
S26-S37/39
危险标志:
Xi: Irritant;

合成路线查看所有的合成路线

  • 28222-02-8

    5-Nitro-2-phenoxypyridine

  • ~85%

  • 25194-67-6

    6-苯氧基-3-吡啶胺

  • 4487-59-6

    2-溴-5-硝基吡啶

  • 25194-67-6

    6-苯氧基-3-吡啶胺

  • 108-95-2

    苯酚

  • 25194-67-6

    6-苯氧基-3-吡啶胺

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US2141000
CHEMICAL NAME :
Pyridine, 5-amino-2-phenoxy-
CAS REGISTRY NUMBER :
25194-67-6
BEILSTEIN REFERENCE NO. :
0140834
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H10-N2-O
MOLECULAR WEIGHT :
186.23
WISWESSER LINE NOTATION :
T6NJ BOR& EZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,153,1947

MSDS 展开↓

Name: 6-Phenoxy-3-pyridinamine 95+% Material Safety Data Sheet
Synonym:
CAS: 25194-67-6
Section 1 - Chemical Product   MSDS Name:6-Phenoxy-3-pyridinamine 95+% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
25194-67-6 6-Phenoxy-3-pyridinamine 95+% unlisted
Hazard Symbols: XN
Risk Phrases: 20/21/22 22 36/37/38

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Harmful if swallowed. Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
  Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 25194-67-6: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Solid
Color: brown
Odor: sweetish odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C11H10N2O
Molecular Weight: 186.21

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Acids, acid chlorides, strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 25194-67-6: US2141000 LD50/LC50:
CAS# 25194-67-6: Oral, mouse: LD50 = 500 mg/kg.
Carcinogenicity:
6-Phenoxy-3-pyridinamine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
IMO
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing group: III

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 25194-67-6: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 25194-67-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 25194-67-6 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

海关数据查看详细

中国海关编码:2933399090

概述:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素:
品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
摘要/Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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