cas号： 13256-32-1 ，名称： N,N'-二甲基亚硝基脲的性质/作用/用途-化学加百科

N,N'-二甲基亚硝基脲

N,N'-二甲基亚硝基脲基本信息
CAS号	13256-32-1	分子式	C3H7N3O2
分子量	117.10700	精确质量	117.05400
PSA	61.77000	LogP	0.32990

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基本信息物化性质合成路线毒性上下游

基本信息展开↓

CAS号：: 13256-32-1
3D弹球模型：: 立即前往扯扯看
分子式：: C3H7N3O2
分子量：: 117.10700
中文名称：: N,N'-二甲基亚硝基脲
英文名称：: 1,3-dimethyl-1-nitrosourea
中文别名：: N,N'-二甲基亚硝基脲
英文别名：: 1,3-dimethyl-1-nitrosourea;
N,N'-Dimethylnitrosourea;
1,3 dimethyl 1 nitrosourea;
N-nitroso-1,3-dimethylurea;
Dimethylnitrosourea;
1,3-Dimethylnitrosourea;
N-nitroso-N,N'-dimethylurea;
1,3-Dimethyl-N-nitrosourea;
1,2-Dimethyl-1-nitrosourea;
Nitrosodimethylurea;
N,N'-Dimethyl-N-nitrosourea;
N-Nitrosodimethylurea
精确分子量/精确质量：: 117.05400
极性分子表面积/PSA：: 61.77000
油水分配系数/LogP：: LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值，反映了物质在油水两相中的分配情况。其中、LogP值越大，说明该物质越亲油；反之，LogP值越小，则说明该物质越亲水。
InChI：: The Key: BHMHNSQLZKUIMD-UHFFFAOYSA-N

物化性质展开↓

密度：: 1.25g/cm3
折射率：: 1.505

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534-13-4

N,N′-二甲基硫脲
→

~65%
13256-32-1

N,N'-二甲基亚硝基脲

96-31-1

1,3-二甲基脲
→

~56%
13256-32-1

N,N'-二甲基亚硝基脲

96-31-1

1,3-二甲基脲
+
7782-77-6

亚硝酸
→
13256-32-1

N,N'-二甲基亚硝基脲

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YT0350000

CHEMICAL NAME :: Urea, 1,3-dimethyl-1-nitroso-

CAS REGISTRY NUMBER :: 13256-32-1

BEILSTEIN REFERENCE NO. :: 1756842

LAST UPDATED :: 199612

DATA ITEMS CITED :: 22

MOLECULAR FORMULA :: C3-H7-N3-O2

MOLECULAR WEIGHT :: 117.13

WISWESSER LINE NOTATION :: ONN1&VM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1300 mg/kg/65W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors Peripheral Nerve and Sensation - peripheral nerve tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 836 mg/kg/20W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Brain and Coverings - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 660 mg/kg/66W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors Peripheral Nerve and Sensation - peripheral nerve tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 720 mg/kg/9W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Blood - lymphoma, including Hodgkin's disease

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 680 mg/kg/17W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 56222 mg/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

DOSE :: 20 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 10 mg/kg

SEX/DURATION :: female 13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 50 mg/kg

SEX/DURATION :: female 9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: DNA inhibition

MUTATION DATA

TYPE OF TEST :: Host-mediated assay

TEST SYSTEM :: Rodent - mouse Ascites tumor

DOSE/DURATION :: 100 mg/kg

REFERENCE :: EKSODD Eksperimental'naya Onkologiya. Experimental Oncology. (V/O Mezhdunarodnaya Kniga, 113095 Mosow, USSR) V.1- 1979- Volume(issue)/page/year: 8(3),70,1986