尼泊金乙酯钠盐

尼泊金乙酯钠盐 基本信息
CAS号 35285-68-8 分子式 C9H9NaO3
分子量 188.15600 精确质量  188.04500
PSA  49.36000 LogP  2.00710

基本信息 展开↓

CAS号:
35285-68-8
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分子式:
C9H9NaO3
分子量:
188.15600
中文名称:
尼泊金乙酯钠盐
英文名称:
sodium,4-ethoxycarbonylphenolate
中文别名:
尼泊金乙酯钠盐;
羟苯乙酯钠;
尼泊金乙酯钠;
4-羟基苯甲酸乙酯钠盐;
对羟基苯甲酸乙酯钠
英文别名:
sodium,4-ethoxycarbonylphenolate;
Ethyl p-hydroxybenzoate,sodium salt;
sodium 4-carboethoxyphenolate;
Ethylparaben,sodium salt;
EINECS 252-487-6;
4-Hydroxy-benzoesaeure-aethylester,Natrium-Salz;
ethyl 4-hydroxybenzoate sodium salt;
UNII-Z0D00IVA10;
Sodium ethylparaben;
4-Hydroxybenzoic acid,ethyl ester,sodium salt;
Sodium ethyl p-hydroxybenzoate;
Sodium 4-ethoxycarbonylphenoxide;
Sodium 4-(ethoxycarbonyl)phenolate;
sodium salt of ethyl-4-hydroxybenzoate;
sodium salt of p-hydroxy ethylbenzoate
精确分子量/精确质量:
188.04500
极性分子表面积/PSA:
49.36000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
EINECS:
252-487-6
InChI:
InChI=1/C9H10O3.Na/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6,10H,2H2,1H3;/q;+1

生产制备方法及用途展开↓

制备方法


本品为水溶性防腐剂,主要特点是安全、高效、广谱抗菌。广泛应用于医药工业 (中草药、中成药剂的配制;医疗器械消毒);食品工业(乳制品、腌制品、饮料、果 汁、果冻、糕点等);纺织工业(纺织品、棉纱、化纤)的防腐。以及其他如化妆品、 饲料、日用工业品的防腐。20公斤纸板桶,内复合铝膜袋。

用途简介


物化性质展开↓

沸点:
297.5ºC at 760 mmHg
闪点:
120.3ºC

安全信息展开↓

海关代码:
2909500000

合成路线查看所有的合成路线

  • 1268380-09-1

    1268380-09-1

  • ~99%

  • 81256-74-8

    sodium salicylat

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  • 35285-68-8

    尼泊金乙酯钠盐

  • 120-47-8

    尼泊金乙酯

  • 35285-68-8

    尼泊金乙酯钠盐

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DH2200000
CHEMICAL NAME :
Benzoic acid, p-hydroxy-, ethyl ester, sodium deriv.
CAS REGISTRY NUMBER :
35285-68-8
LAST UPDATED :
199107
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H9-O3.Na
MOLECULAR WEIGHT :
188.17
WISWESSER LINE NOTATION :
OR DVO2 &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
520 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Behavioral - ataxia
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956

MSDS 展开↓


Section 1. Chemical Product and Company Identification
    Ethylparaben Sodium
    Common Name/
    Trade Name
    Ethylparaben Sodium

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water    
    for at least 15 minutes. Get medical attention if irritation occurs.
    Skin Contact        Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation    
    develops.
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.    
    Get medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to    
    an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention
    if symptoms appear.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Not available.
    Flash Points
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2).    
    Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
    Various Substances
    Risks of explosion of the product in presence of mechanical impact: Not available.
    Explosion Hazards in
    Risks of explosion of the product in presence of static discharge: Not available.
    Presence of Various
    Substances
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
    and Instructions
    Special Remarks on        As with most organic solids, fire is possible at elevated temperatures    
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    requirements.
    Large Spill        Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading    
    water on the contaminated surface and allow to evacuate through the sanitary system.

Section 7. Handling and Storage
    Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do
    Precautions
    not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or
    the label. Keep away from incompatibles such as oxidizing agents, reducing agents.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area.    
    Ethylparaben Sodium

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels    
    below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
    exposure to airborne contaminants below the exposure limit.
    Personal Protection        Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.    
    Gloves.
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
    a Large Spill        used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a    
    specialist BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Crystals solid.)        Odor        Not available.    
    Taste        Not available.    
    Molecular Weight        188.17 g/mole    
    Off-white.
    Color
    Not available.
    pH (1% soln/water)
    Boiling Point        Not available.    
    Not available.
    Melting Point
    Critical Temperature        Not available.    
    Not available.
    Specific Gravity
    Vapor Pressure        Not applicable.    
    Vapor Density        Not available.    
    Not available.
    Volatility
    Odor Threshold        Not available.    
    Not available.
    Water/Oil Dist. Coeff.
    Ionicity (in Water)        Not available.    
    Dispersion Properties        Not available.    
    Solubility        Not available.    

Section 10. Stability and Reactivity Data
    Stability        The product is stable.    
    Not available.
    Instability Temperature
    Conditions of Instability        Excess heat, incompatible materials    
    Incompatibility with various Reactive with oxidizing agents, reducing agents.
    substances
    Corrosivity        Not available.    
    Special Remarks on        Not available.    
    Reactivity
    Special Remarks on        Not available.    
    Corrosivity
    Polymerization        Will not occur.    
    Ethylparaben Sodium

Section 11. Toxicological Information
    Routes of Entry        Inhalation. Ingestion.    
    Toxicity to Animals        Acute oral toxicity (LD50): 2500 mg/kg [Mouse].    
    Chronic Effects on Humans Not available.
    Other Toxic Effects on        Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.    
    Humans
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        Not available.    
    Chronic Effects on Humans
    Special Remarks on other        Acute Potential Health Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation.    
    Eyes: May cause eye irritation.
    Inhalation: Dust may cause respiratory tract irritation.
    Ingestion: Expected to be a low hazard. May affect behavior/central nervous system/nervous system
    (ataxia, somnolence, flaccid paralysis)

Section 12. Ecological Information
    Not available.
    Ecotoxicity
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation    
    products may arise.
    Toxicity of the Products        The product itself and its products of degradation are not toxic.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Identification        Not applicable.    
    Special Provisions for        Not applicable.    
    Transport
    DOT (Pictograms)
    Ethylparaben Sodium

Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    Regulations
    California        California prop. 65: This product contains the following ingredients for which the State of California has    
    Proposition 65        found to cause cancer which would require a warning under the statute: No products were found.    
    Warnings
    California prop. 65: This product contains the following ingredients for which the State of California has
    found to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS    
    No. 252-487-6).
    Canada: Listed on Canadian Domestic Substance List (DSL).
    China: Listed on National Inventory.
    Japan: Listed on National Inventory (ENCS).
    Korea: Not listed on National Inventory (KECI).
    Philippines: Listed on National Inventory (PICCS).
    Australia: Listed on AICS.
    Other Classifications        WHMIS (Canada) Not controlled under WHMIS (Canada).    
    DSCL (EEC)        This product is not classified        Not applicable.    
    according to the EU regulations.
    Health Hazard
    HMIS (U.S.A.)        1 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    1 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or
    equivalent.
    Ethylparaben Sodium


SECTION 16 - ADDITIONAL INFORMATION
N/A

海关数据查看详细

中国海关编码:2909500000

概述:
2909500000. 醚酚、醚醇酚及其卤化、磺化、硝化或亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
申报要素:
品名, 成分含量, 用途
摘要/Summary:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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    尼泊金乙酯

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