CHEMICAL IDENTIFICATION

RTECS NUMBER :

KD1600000

CHEMICAL NAME :

2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-8-carboxaldehyd e, 1,2-dihydro-5, 6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,2 2-heptamethyl-1,11-di oxo-, 21-acetate

CAS REGISTRY NUMBER :

13292-22-3

LAST UPDATED :

199703

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C38-H47-N-O13

MOLECULAR WEIGHT :

725.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

907 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4002754

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

416 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4002754

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

299 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977