CHEMICAL IDENTIFICATION

RTECS NUMBER :

CD2996200

CHEMICAL NAME :

Antipyrine, 4-(4-(3-methyl-2-phenylmorpholino)methyl)-, hydrochloride

CAS REGISTRY NUMBER :

50321-35-2

LAST UPDATED :

198703

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C23-H27-N3-O2.Cl-H

MOLECULAR WEIGHT :

413.99

WISWESSER LINE NOTATION :

T6N DOTJ B1 CR& A1- DT5NNVJ A1 BR& E1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

260 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 49,298,1960

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

115 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold

REFERENCE :

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,421,1958