次亚磷酸钠

次亚磷酸钠 基本信息
CAS号 10039-56-2 分子式 H2NaO3P
分子量 103.97800 精确质量  103.96400
PSA  83.50000 LogP  0.55930

基本信息 展开↓

CAS号:
10039-56-2
3D弹球模型:
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分子式:
H2NaO3P
分子量:
103.97800
中文名称:
次亚磷酸钠
英文名称:
Sodium hypophosphite monohydrate
中文别名:
次亚磷酸钠;
次磷酸钠单水
英文别名:
Sodium hypophosphite monohydrate;
Sodium Hypophosphite Monohydrate;
Sodiumhypophosphitemonohydrate;
Fosfornan sodny [Czech]
精确分子量/精确质量:
103.96400
极性分子表面积/PSA:
83.50000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
贝尔斯坦号/MDL:
MFCD00149207
EINECS:
231-669-9
PubChem:
24855944
InChI:
The Key: SIGUVTURIMRFDD-UHFFFAOYSA-M

生产制备方法及用途展开↓

制备方法


1.将黄磷 ( 或白磷) 、过量的氢氧化钙水溶液于98℃下进行反应: 反应中生的磷化氢引出后用10%的硫酸铜溶液吸收 ( 要注意安全! ) 。反应结束后,冷却,通入二氧化碳至溶液ph值为7.5~8.0,沉淀出过量氢氧化钙。滤出沉淀并用水洗涤数次,洗液并入滤液,然后分次少量加入20%的碳酸钠溶液至溶液对酚酞呈弱碱性: 过滤,滤液真空蒸发浓缩至密度为1.16时,重新过滤。滤液第二次蒸发浓缩至出现结晶薄膜,冷却结晶,甩干后,于80~95℃干燥,可制得次磷酸钠。母液可回收利用。

合成制备方法


1.将黄磷 ( 或白磷) 、过量的氢氧化钙水溶液于98℃下进行反应:

反应中生的磷化氢引出后用10%的硫酸铜溶液吸收 ( 要注意安全! ) 。反应结束后,冷却,通入二氧化碳至溶液ph值为7.5~8.0,沉淀出过量氢氧化钙。滤出沉淀并用水洗涤数次,洗液并入滤液,然后分次少量加入20%的碳酸钠溶液至溶液对酚酞呈弱碱性:

过滤,滤液真空蒸发浓缩至密度为1.16时,重新过滤。滤液第二次蒸发浓缩至出现结晶薄膜,冷却结晶,甩干后,于80~95℃干燥,可制得次磷酸钠。
母液可回收利用。

用途简介


用作分析试剂,常用作强还原剂,也用于临床检验及电镀。

用途


1.用作分析试剂,常用作强还原剂,也用于临床检验及电镀。

物化性质展开↓

外观与性状:
无气味的白色晶体在室温中
密度:
0.8 g/cm3 (20ºC)
熔点:
90°C
水溶解性:
1000 g/L (20 ºC)
存储条件/存储方法:

 

稳定性相关:

具有强还原性,与氯酸盐和氧化剂接触能爆炸。

其它信息:

1.       性状:白色无气味粉末。

2.       密度(g/mL,25℃):1.86

3.       相对蒸汽密度(g/mL,空气=1):未确定

4.       熔点(ºC):248

5.       沸点(ºC,常压):未确定

6.       沸点(ºC,5.2kPa):未确定

7.       折射率:未确定

8.       闪点(ºC):未确定

9.       比旋光度(º):未确定

10.    自燃点或引燃温度(ºC):未确定

11.    蒸气压(kPa,20ºC):未确定

12.    饱和蒸气压(kPa,60ºC):未确定

13.    燃烧热(KJ/mol):未确定

14.    临界温度(ºC):未确定

15.    临界压力(KPa):未确定

16.    油水(辛醇/水)分配系数的对数值:未确定

17.    爆炸上限(%,V/V):未确定

18.    爆炸下限(%,V/V):未确定

19.    溶解性:溶于水1000 g/L (20 ºC)。溶液醇和甘油,微溶于无水乙醇,不溶于醚。

安全信息展开↓

海关代码:
2835100000
WGK_Germany:
3
德国有关水污染物质的分类清单
安全说明:
S22-S24/25
RTECS号:
SZ5640000

合成路线查看所有的合成路线

  • 10039-56-2

    次亚磷酸钠

  • 10039-56-2

    次亚磷酸钠

  • +

  • 7732-18-5

  • 10049-21-5

    磷酸二氢钠单水合物

  • 10039-56-2

    次亚磷酸钠

  • 12185-10-3

    黄磷

  • 10039-56-2

    次亚磷酸钠

化学图谱

  1. 次磷酸钠单水红外图谱(IR1)

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毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SZ5640000
CHEMICAL NAME :
Phosphinic acid, sodium salt, monohydrate
CAS REGISTRY NUMBER :
10039-56-2
LAST UPDATED :
199404
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
H2-O2-P.Na.H2-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,16,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T1724 No. of Facilities: 8 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 23 (estimated)
毒理学数据:

1、急性毒性:大鼠经口LD50:7640 mg/kg

生态数据:

通常对水体是稍微有害的,不要将未稀释或大量产品接触地下水,水道或污水系统,未经政府许可勿将材料排入周围环境。

MSDS 展开↓

Name: Sodium Hypophosphite Monohydrate 99% Material Safety Data Sheet
Synonym: Phosphinic Acid Sodium Salt Monohydrate; Sodium Hypophosphite Monohydrat
CAS: 10039-56-2
Section 1 - Chemical Product   MSDS Name:Sodium Hypophosphite Monohydrate 99% Material Safety Data Sheet
Synonym:Phosphinic Acid Sodium Salt Monohydrate; Sodium Hypophosphite Monohydrat

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
10039-56-2 Sodium Hypophosphite Monohydrate >98 unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Combustion generates toxic fumes.
Decomposes generating flammable and toxic phosphine gas.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Solid
Appearance: white
Odor: odorless
pH: Not available.
Vapor Pressure: Negligible
Viscosity: Not available.
Boiling Point: Decomposes
Freezing/Melting Point: 90 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature: >90 C
Solubility in water: Soluble in water
Specific Gravity/Density: 0.8
Molecular Formula: NaH2PO2.H20
Molecular Weight: 87.9764

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable. However, may decompose if heated.
Conditions to Avoid:
High temperatures, incompatible materials, dust generation, moisture.
Incompatibilities with Other Materials:
Strong oxiziders, moisture.
Hazardous Decomposition Products:
Phosphine, irritating and toxic fumes and gases, toxic fumes of sodium oxide, hydrogen gas.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 10039-56-2: SZ5640000 LD50/LC50:
CAS# 10039-56-2: Oral, rat: LD50 = 7640 mg/kg.
Carcinogenicity:
Sodium Hypophosphite Monohydrate - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Other No information available.

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Dangerous Goods Code:
UN Number:

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 10039-56-2: 2
United Kingdom Occupational Exposure Limits
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 10039-56-2 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
US FEDERAL
TSCA
CAS# 10039-56-2 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

分子结构与计算化学数据展开↓

分子结构数据


1、摩尔折射率:无可用的

2、摩尔体积(cm3/mol):无可用的

3、等张比容(90.2K):无可用的

4、表面张力(dyne/cm):无可用的

5、介电常数:无可用的

6、极化率(10-24cm3):无可用的

7、单一同位素质量:103.963925 Da

8、标称质量:104 Da

9、平均质量:103.9776 Da

计算化学数据


1、   疏水参数计算参考值(XlogP):-1.2

2、   氢键供体数量:0

3、   氢键受体数量:2

4、   可旋转化学键数量:0

5、   拓扑分子极性表面积(TPSA):40.1.

6、   重原子数量:3

7、   表面电荷:-1

8、   复杂度:7.5

9、   同位素原子数量:0

10、   确定原子立构中心数量:0

11、   不确定原子立构中心数量:0

12、   确定化学键立构中心数量:0

13、   不确定化学键立构中心数量:0

14、   共价键单元数量:1

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