CHEMICAL IDENTIFICATION

RTECS NUMBER :

YS4981000

CHEMICAL NAME :

Urea, 1-(2-chloroethyl)-3-(beta-D-glucopyranosyl)-1-nitroso -

CAS REGISTRY NUMBER :

58484-07-4

LAST UPDATED :

199112

DATA ITEMS CITED :

8

MOLECULAR FORMULA :

C9-H16-Cl-N3-O7

MOLECULAR WEIGHT :

313.73

WISWESSER LINE NOTATION :

T6OTJ BMVNNO&2G CQ DQ EQ F1Q -B,D-GLU

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

40 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

15 mg/kg

TOXIC EFFECTS :

Tumorigenic - active as anti-cancer agent

TYPE OF TEST :

LD10 - Lethal Dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

10 mg/kg

TOXIC EFFECTS :

Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :

DNA inhibition

TEST SYSTEM :

Rodent - mouse Leukocyte

DOSE/DURATION :

10 umol/L

REFERENCE :

CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 37,783,1977