CHEMICAL IDENTIFICATION

RTECS NUMBER :

DI9450000

CHEMICAL NAME :

Benzo(c)phenanthrene, 5-methyl-

CAS REGISTRY NUMBER :

652-04-0

BEILSTEIN REFERENCE NO. :

2329427

LAST UPDATED :

199612

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C19-H14

MOLECULAR WEIGHT :

242.33

WISWESSER LINE NOTATION :

L C6 B666J I1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

10 gm/kg/51W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

REFERENCE :

PRLBA4 Proceedings of the Royal Society of London, Series B: Biological Sciences. (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 1905- Volume(issue)/page/year: 129,439,1940

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

480 mg/kg/17W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :

PRLBA4 Proceedings of the Royal Society of London, Series B: Biological Sciences. (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 1905- Volume(issue)/page/year: 123,343,1937

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1800 mg/kg/27W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :

PRLBA4 Proceedings of the Royal Society of London, Series B: Biological Sciences. (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 1905- Volume(issue)/page/year: 129,439,1940

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

10 mg/kg

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :

JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 1,225,1940