Norscopolamine hydrochloride

Norscopolamine hydrochloride 基本信息
CAS号 24676-80-0 分子式 C16H20ClNO4
分子量 325.78700 精确质量  325.10800
PSA  71.09000 LogP  1.70670

基本信息 展开↓

CAS号:
24676-80-0
3D弹球模型:
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分子式:
C16H20ClNO4
分子量:
325.78700
英文名称:
Norscopolamine hydrochloride
英文别名:
Norscopolamine hydrochloride;
norscopolamine,hydrochloride;
(S)-3-hydroxy-2-phenyl-propionic acid (1rN,2tH,4tH,5cN)-3-oxa-9-aza-tricyclo[3.3.1.02,4]non-7t-yl ester,hydrochloride;
Norscopolamin-hydrochlorid
精确分子量/精确质量:
325.10800
极性分子表面积/PSA:
71.09000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
InChI:
The Key: PMDQSBZXEATWCG-QKUYDHLLSA-N

物化性质展开↓

沸点:
474.7ºC at 760mmHg
闪点:
240.9ºC
蒸汽压:
8.13E-10mmHg at 25°C

合成路线查看所有的合成路线

  • 114-49-8

    东莨菪碱氢溴酸盐

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  • 24676-80-0

    Norscopolamine hydrochloride

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RD1575000
CHEMICAL NAME :
1-alpha-H,5-alpha-H-Nortropan-3-alpha-ol, 6-beta,7-beta-epoxy-, (-)-tropate, hydrochloride
CAS REGISTRY NUMBER :
24676-80-0
LAST UPDATED :
199109
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C16-H19-N-O4.Cl-H
MOLECULAR WEIGHT :
325.82

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3020 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4230 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraduodenal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
860 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969

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