CHEMICAL IDENTIFICATION

RTECS NUMBER :

TL9900000

CHEMICAL NAME :

1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)thioxanthen-9-ylidene)propyl )-

CAS REGISTRY NUMBER :

2709-56-0

LAST UPDATED :

199507

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C23-H25-F3-N2-O-S

MOLECULAR WEIGHT :

434.56

WISWESSER LINE NOTATION :

T C666 BS IYJ IU3- AT6N DNTJ D2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - child

DOSE/DURATION :

900 ug/kg

TOXIC EFFECTS :

Behavioral - sleep Behavioral - changes in motor activity (specific assay) Behavioral - coma

REFERENCE :

DICPBB Drug Intelligence and Clinical Pharmacy. (POB 42435, Cincinnati, OH 45242) V.3- 1969- Volume(issue)/page/year: 15,388,1981

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human

DOSE/DURATION :

367 ug/kg/12D-I

TOXIC EFFECTS :

Behavioral - wakefulness Behavioral - muscle weakness Behavioral - headache

REFERENCE :

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,93,1972

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

150 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,2121,1977