羟哌氯丙嗪亚砜氯吩嗪亚砜

羟哌氯丙嗪亚砜氯吩嗪亚砜 基本信息
CAS号 10078-25-8 分子式 C21H26ClN3O2S
分子量 419.96800 精确质量 　419.14300
PSA 　66.23000 LogP 　3.76470
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目录
基本信息 物化性质 合成路线 毒性 上下游

基本信息 展开↓

CAS号：
10078-25-8
3D弹球模型：
立即前往扯扯看
分子式：
C21H26ClN3O2S
分子量：
419.96800
中文名称：
羟哌氯丙嗪亚砜氯吩嗪亚砜
英文名称：
PERPHENAZINE SULFOXIDE (100 MG)
中文别名：
羟哌氯丙嗪亚砜氯吩嗪亚砜
英文别名：
PERPHENAZINE SULFOXIDE (100 MG);
4-(3-(2-chlorophenothiazin-10-yl)propyl)-1-piperazineethanosulfoxide;
2-chloro-10-(3-(4-(2-hydroxyethyl)-7-piperazinyl)propyl)phenothiazine;
10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl]-2-chloro-10H-phenothiazine 5-oxide;
etaperazine S-oxide;
1-Piperazineethanol,4-(3-(2-chlorophenothiazin-10-yl)propyl)-,sulfoxide;
Perphenazine Sulfate;
perphenazine sulfoxide;
Perphenazinsulfoxid;
perpherazine sulfoxide
精确分子量/精确质量：
419.14300
极性分子表面积/PSA：
66.23000
油水分配系数/LogP：

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值，反映了物质在油水两相中的分配情况。其中、LogP值越大，说明该物质越亲油；反之，LogP值越小，则说明该物质越亲水。
InChI：
The Key: WXJXTMQMAOYROI-UHFFFAOYSA-N

物化性质展开↓

密度：
1.41g/cm3
沸点：
624.8ºC at 760mmHg
闪点：
331.7ºC
折射率：
1.71
蒸汽压：
1.78E-16mmHg at 25°C

合成路线查看所有的合成路线

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    羟哌氯丙嗪亚砜；氯吩嗪亚砜

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL7700000
CHEMICAL NAME :
1-Piperazineethanol, 4-(3-(2-chlorophenothiazin-10-yl)propyl)-, sulfoxide
CAS REGISTRY NUMBER :
10078-25-8
LAST UPDATED :
199612
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C21-H26-Cl-N3-O2-S
MOLECULAR WEIGHT :
420.01
WISWESSER LINE NOTATION :
T C666 BN ISJ EG IO B3- AT6N DNTJ D2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
127 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
69 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,638,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
68 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Bird - pigeon
DOSE/DURATION :
52500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Bird - pigeon
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972

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