CHEMICAL IDENTIFICATION

RTECS NUMBER :

YT7750000

CHEMICAL NAME :

Urea, 1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)et hyl)-2-thio-

CAS REGISTRY NUMBER :

34839-70-8

LAST UPDATED :

198703

DATA ITEMS CITED :

5

MOLECULAR FORMULA :

C9-H16-N4-S2

MOLECULAR WEIGHT :

244.41

WISWESSER LINE NOTATION :

T5M CNJ D1S2MYUS&M1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1493 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

142 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2642 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

130 mg/kg

TOXIC EFFECTS :

Behavioral - antipsychotic Lungs, Thorax, or Respiration - respiratory depression

MUTATION DATA

TYPE OF TEST :

DNA inhibition

TEST SYSTEM :

Human Cells - not otherwise specified

DOSE/DURATION :

1 umol/L

REFERENCE :

JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 65,400,1975