CHEMICAL IDENTIFICATION

RTECS NUMBER :

EC1925000

CHEMICAL NAME :

Biuret, 1-methyl-1-nitroso-

CAS REGISTRY NUMBER :

13860-69-0

BEILSTEIN REFERENCE NO. :

1775240

LAST UPDATED :

199612

DATA ITEMS CITED :

11

MOLECULAR FORMULA :

C3-H6-N4-O3

MOLECULAR WEIGHT :

146.13

WISWESSER LINE NOTATION :

ZVMVN1&NO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

450 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

25 mg/kg

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1300 mg/kg/1Y-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors Gastrointestinal - tumors

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1200 mg/kg/1Y-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors Gastrointestinal - tumors

MUTATION DATA

TYPE OF TEST :

Mutation in microorganisms

TEST SYSTEM :

Microorganism - not otherwise specified

DOSE/DURATION :

1 pph

REFERENCE :

ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 27,738,1982