7-去氮肌苷

7-去氮肌苷 基本信息
CAS号 2862-16-0 分子式 C11H13N3O5
分子量 267.23800 精确质量 　267.08600
PSA 　120.60000 LogP 　-1.66390
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等价的CAS号：

2862-16-0,72565-06-1,72565-07-2,95709-08-3
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目录
基本信息 物化性质 合成路线 毒性 上下游

基本信息 展开↓

CAS号：
2862-16-0
3D弹球模型：
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分子式：
C11H13N3O5
分子量：
267.23800
中文名称：
7-去氮肌苷
英文名称：
4H-Pyrrolo[2,3-d]pyrimidin-4-one,1,7-dihydro-7-b-D-ribofuranosyl-(8CI,9CI)
中文别名：
7-去氮肌苷
英文别名：
4H-Pyrrolo[2,3-d]pyrimidin-4-one,1,7-dihydro-7-b-D-ribofuranosyl-(8CI,9CI);
Antibiotic XK-101-2;
7-Deazainosine
精确分子量/精确质量：
267.08600
极性分子表面积/PSA：
120.60000
油水分配系数/LogP：

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值，反映了物质在油水两相中的分配情况。其中、LogP值越大，说明该物质越亲油；反之，LogP值越小，则说明该物质越亲水。
InChI：
The Key: DPRSKJHWKNHBOW-KCGFPETGSA-N

物化性质展开↓

密度：
1.9g/cm3
沸点：
624.8ºC at 760mmHg
闪点：
331.7ºC
折射率：
1.81
蒸汽压：
1.78E-16mmHg at 25°C

合成路线查看所有的合成路线

  • 16754-81-7

    2-Amino-4-methoxy-6-trifluoromethyl-1,3,5-triazine

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  • 2862-16-0

    7-去氮肌苷

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY9450000
CHEMICAL NAME :
7H-Pyrrolo(2,3-d)pyrimidin-4-ol, 7-beta-D-ribofuranosyl-
CAS REGISTRY NUMBER :
2862-16-0
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C11-H13-N3-O5
MOLECULAR WEIGHT :
267.27
WISWESSER LINE NOTATION :
T56 BN GN INJ FQ I- BT5OTJ CQ DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
26 mg/kg
TOXIC EFFECTS :
Gastrointestinal - peritonitis Liver - hepatitis (hepatocellular necrosis), zonal Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,116,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Gastrointestinal - peritonitis Liver - hepatitis (hepatocellular necrosis), zonal Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,116,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
24 mg/kg
TOXIC EFFECTS :
Gastrointestinal - peritonitis Liver - hepatitis (hepatocellular necrosis), zonal Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,116,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Gastrointestinal - peritonitis Liver - hepatitis (hepatocellular necrosis), zonal Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,116,1969
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
48 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Skin and Appendages - dermatitis, other (after systemic exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,116,1969
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
48 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Skin and Appendages - dermatitis, other (after systemic exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,116,1969

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