芳香法宗

芳香法宗 基本信息
CAS号 22881-35-2 分子式 C24H31N3O
分子量 377.52200 精确质量  377.24700
PSA  30.17000 LogP  4.36240

基本信息 展开↓

CAS号:
22881-35-2
3D弹球模型:
立即前往扯扯看
分子式:
C24H31N3O
分子量:
377.52200
中文名称:
芳香法宗
英文名称:
1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one
中文别名:
芳香法宗;
泛普法宗
英文别名:
1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one;
Famprofazone;
Famprofazona [INN-Spanish];
Famprofazonum [INN-Latin]
精确分子量/精确质量:
377.24700
极性分子表面积/PSA:
30.17000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
EINECS:
245-284-9
InChI:
The Key: GNUXVOXXWGNPIV-UHFFFAOYSA-N

物化性质展开↓

密度:
1.083g/cm3
沸点:
485.1ºC at 760mmHg
闪点:
184.8ºC
折射率:
1.574
蒸汽压:
1.45E-09mmHg at 25°C

安全信息展开↓

危险类别码:
22
安全说明:
36
RTECS号:
UQ9451000
危险标志:
Xn: Harmful;

合成路线查看所有的合成路线

  • 88913-09-1

    5-[[hydroxy-(2-methyl-1-phenylpropan-2-yl)amino]methyl]-1-methyl-2-phenyl-4-propan-2-ylpyrazol-3-one

  • 300-57-2

    烯丙基苯

  • +

  • 4075-96-1

    1-phenyl-2-dimethylaminopropane

  • +

  • 22881-35-2

    芳香法宗

  • +

  • 88913-10-4

    3H-Pyrazol-3-one,1,2-dihydro-5-[(hydroxymethylamino)methyl]-1-methyl-4-(1-methylethyl)-2-phenyl-

  • +

  • 83957-93-1

    3-Formyl-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-on

  • +

  • 83957-94-2

    4-Isopropyl-2-methyl-3-(N-methyl-aminomethyl)-1-phenyl-3-pyrazolin-5-on

  • 88913-09-1

    5-[[hydroxy-(2-methyl-1-phenylpropan-2-yl)amino]methyl]-1-methyl-2-phenyl-4-propan-2-ylpyrazol-3-one

  • 4075-96-1

    1-phenyl-2-dimethylaminopropane

  • +

  • 22881-35-2

    芳香法宗

  • +

  • 83957-93-1

    3-Formyl-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-on

  • +

  • 83957-94-2

    4-Isopropyl-2-methyl-3-(N-methyl-aminomethyl)-1-phenyl-3-pyrazolin-5-on

  • +

  • 88913-08-0

    88913-08-0

毒理性展开↓

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ9451000
CHEMICAL NAME :
Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)m ethylamino)methyl-
CAS REGISTRY NUMBER :
22881-35-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C24-H31-N3-O
MOLECULAR WEIGHT :
377.58
WISWESSER LINE NOTATION :
T5NNVJ A1 BR& DY1&1 E1N1&Y1&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SMWOAS Schweizerische Medizinische Wochenschrift. (Schwabe & Co., Steintorst 13, 4010 Basel, Switzerland) V.50- 1920- Volume(issue)/page/year: 84,351,1954

MSDS 展开↓


Section 1. Chemical Product and Company Identification
    Famprofazone
    Common Name/
    Trade Name
    Famprofazone

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at    
    least 15 minutes. Get medical attention if irritation occurs.
    Skin Contact        Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.    
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an    
    unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
    clothing such as a collar, tie, belt or waistband.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).    
    Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    Risks of explosion of the product in presence of static discharge: Not available.
    of Various Substances
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    As with most organic solids, fire is possible at elevated temperatures
    Special Remarks on
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    requirements.
    Large Spill        Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water    
    on the contaminated surface and allow to evacuate through the sanitary system.
    Famprofazone

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not    
    ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately and
    show the container or the label.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area.    

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.    
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist    
    BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid.        Odor        Not available.    
    Taste        Not available.    
    Molecular Weight        377.5 g/mole    
    Color        Not available.    
    pH (1% soln/water)        Not available.    
    Not available.
    Boiling Point
    Melting Point        Not available.    
    Not available.
    Critical Temperature
    Specific Gravity        Not available.    
    Vapor Pressure        Not applicable.    
    Vapor Density        Not available.    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Ionicity (in Water)        Not available.    
    Dispersion Properties        Not available.    
    Solubility        Not available.    

Section 10. Stability and Reactivity Data
    The product is stable.
    Stability
    Instability Temperature        Not available.    
    Conditions of Instability        Excess heat    
    Not available.
    Incompatibility with various
    substances
    Not available.
    Corrosivity
    Famprofazone
    Not available.
    Special Remarks on
    Reactivity
    Not available.
    Special Remarks on
    Corrosivity
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Inhalation. Ingestion.    
    Toxicity to Animals        Acute oral toxicity (LD50): 2000 mg/kg [Mouse].    
    Chronic Effects on Humans Not available.
    Other Toxic Effects on        Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.    
    Humans
    Special Remarks on
    Not available.
    Toxicity to Animals
    Special Remarks on        Not available.    
    Chronic Effects on Humans
    Special Remarks on other        Acute Potential Health Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation.    
    Eyes: May cause eye irritation.
    Inhalation: May cause respiratory tract irritation.
    Ingestion: May be harmful if swallowed.

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    Not available.
    BOD5 and COD
    Possibly hazardous short term degradation products are not likely. However, long term degradation products may
    Products of Biodegradation
    arise.
    Toxicity of the Products        The products of degradation are less toxic than the product itself.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Not applicable.
    Identification
    Special Provisions for        Not applicable.    
    Transport
    Famprofazone
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    Regulations
    California        California prop. 65: This product contains the following ingredients for which the State of California has found    
    to cause cancer which would require a warning under the statute: No products were found.
    Proposition 65
    Warnings
    California prop. 65: This product contains the following ingredients for which the State of California has found
    to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.    
    Other Classifications        WHMIS (Canada) Not available    
    DSCL (EEC)        R22- Harmful if swallowed.        S36- Wear suitable protective clothing.    
    Health Hazard
    HMIS (U.S.A.)        1 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    1 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or
    equivalent.
    Famprofazone


SECTION 16 - ADDITIONAL INFORMATION
N/A

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    5-[[hydroxy-(2-methyl-1-phenylpropan-2-yl)amino]methyl]-1-methyl-2-phenyl-4-propan-2-ylpyrazol-3-one

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