4-甲基-2-(3-吡啶)-1,3-噻唑-5-羧酸乙酯

4-甲基-2-(3-吡啶)-1,3-噻唑-5-羧酸乙酯 基本信息
CAS号 39091-00-4 分子式 C12H12N2O2S
分子量 248.30100 精确质量  248.06200
PSA  80.32000 LogP  2.69020

基本信息 展开↓

CAS号:
39091-00-4
3D弹球模型:
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分子式:
C12H12N2O2S
分子量:
248.30100
中文名称:
4-甲基-2-(3-吡啶)-1,3-噻唑-5-羧酸乙酯
英文名称:
ethyl 4-methyl-2-pyridin-3-yl-1,3-thiazole-5-carboxylate
中文别名:
4-甲基-2-(3-吡啶)-1,3-噻唑-5-羧酸乙酯;
4-甲基-2-(3-吡啶基)噻唑-5-羧酸乙酯;
2,4,6-tri(propan-2-yl)benzenesulfonohydrazide;
2,4,6-triisopropylbenzenesulfono hydrazide;
Ethyl 2-chloro-6-methyl-3-pyridinecarboxylate;
Ethyl 2-chloro-6-methylnicotinate;
ethyl 2-chloro-6-methylpyridine-3-carboxylate;
T6NJ BG CVO2 F1;
4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol;
(3R,4R,4aR,6aS,8S,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol;
(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol;
Aphidicolin;
prostaglandin F(2)(alpha) tris salt;
MK 231;
Mobilin;
Reumofil;
Sudac;
Sulindac sulfoxide;
Sulindaco;
Sulindacum;
Sulinol;
Sulreuma;
UNII-184SNS8VUH;
cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid;
cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid;
cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidenyl)indene-3-acetic acid;
cis-Sulindac;
{5-fl
英文别名:
ethyl 4-methyl-2-pyridin-3-yl-1,3-thiazole-5-carboxylate;
ethyl 4-methyl-2-(pyridin-3-yl)-5-thiazolecarboxylate;
Ethyl 4-methyl-2-(pyridin-3-yl)thiazole-5-carboxylate;
Ethyl 4-methyl-2-(3-pyridinyl)-1,3-thiazole-5-carboxylate;
4-methyl-2-pyridin-3-yl-thiazole-5-carboxylic acid ethyl ester;
ethyl 4-methyl-2-(3-pyridyl)-5-thiazolecarboxylate
精确分子量/精确质量:
248.06200
极性分子表面积/PSA:
80.32000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
InChI:
The Key: PNJYSPUXYJWHJJ-UHFFFAOYSA-N

物化性质展开↓

熔点:
82-84ºC

安全信息展开↓

海关代码:
2934100090
安全说明:
S24/25

合成路线查看所有的合成路线

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    巯基尼古胺

  • +

  • 609-15-4

    2-氯乙酰乙酸乙酯

  • 39091-00-4

    4-甲基-2-(3-吡啶)-1,3-噻唑-5-羧酸乙酯

MSDS 展开↓

Name: Ethyl 4-methyl-2-pyridin-3-yl-1 3-thiazole-5-carboxylate Material Safety Data Sheet
Synonym: None Known
CAS: 39091-00-4
Section 1 - Chemical Product   MSDS Name:Ethyl 4-methyl-2-pyridin-3-yl-1 3-thiazole-5-carboxylate Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
39091-00-4 Ethyl 4-methyl-2-pyridin-3-yl-1,3-thia 95+ unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 39091-00-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Solid
Color: beige
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 56-58 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C12H12N2O2S
Molecular Weight: 248.3

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 39091-00-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Ethyl 4-methyl-2-pyridin-3-yl-1,3-thiazole-5-carboxylate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 22 Do not breathe dust.
S 24/25 Avoid contact with skin and eyes.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 39091-00-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 39091-00-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 39091-00-4 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

海关数据查看详细

中国海关编码:2934100090

概述:
2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素:
品名, 成分含量, 用途
摘要/Summary:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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