CHEMICAL IDENTIFICATION

RTECS NUMBER :

DJ8260000

CHEMICAL NAME :

Benzo(a)pyren-6-ol

CAS REGISTRY NUMBER :

33953-73-0

BEILSTEIN REFERENCE NO. :

1982121

LAST UPDATED :

199612

DATA ITEMS CITED :

13

MOLECULAR FORMULA :

C20-H12-O

MOLECULAR WEIGHT :

268.32

WISWESSER LINE NOTATION :

L D6 B6666 2AB TJ JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4280 ug/kg

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

12 mg/kg

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Blood - leukemia Tumorigenic - tumors at site of application

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intradermal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2400 ug/kg

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4290 ug/kg

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :

Mutation in mammalian somatic cells

TEST SYSTEM :

Rodent - hamster Lung

DOSE/DURATION :

5 mg/L

REFERENCE :

CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,3350,1976 *** REVIEWS *** TOXICOLOGY REVIEW ABSYB2 Alfred Benzon Symposium. (Nankodo Co. Ltd., POB 5272, Tokyo International 100-31, Japan) V.1- 1968- Volume(issue)/page/year: 10,261,1977