2',3',5'-三-O-乙酰-2-氨基-6-氯嘌呤核苷

2',3',5'-三-O-乙酰-2-氨基-6-氯嘌呤核苷 基本信息
CAS号 16321-99-6 分子式 C16H18ClN5O7
分子量 427.79600 精确质量  427.08900
PSA  157.75000 LogP  0.96700

基本信息 展开↓

CAS号:
16321-99-6
3D弹球模型:
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分子式:
C16H18ClN5O7
分子量:
427.79600
中文名称:
2',3',5'-三-O-乙酰-2-氨基-6-氯嘌呤核苷
英文名称:
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
中文别名:
2',3',5'-三-O-乙酰-2-氨基-6-氯嘌呤核苷;
9-[2,3,5-三-o-乙酰基-beta-d-呋喃核糖]-2-氨基-6-氯嘌呤;
9-[2,3,5-三-o-乙酰基-Beta-d-呋喃核糖]-2-氨基-6-氯嘌呤
英文别名:
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate;
2',3',5'-Tri-O-acetyl-2-amino-6-chloropurine Riboside;
2-Amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine;
[(2R,3S,4S,5R)-3,4-diacetyloxy-5-(2-amino-6-chloropurin-9-yl)oxolan-2-yl]methyl acetate
精确分子量/精确质量:
427.08900
极性分子表面积/PSA:
157.75000
油水分配系数/LogP:

LogP值指的是某物质在正辛醇/水两相体系中的分配系数的对数值,反映了物质在油水两相中的分配情况。其中、LogP值越大,说明该物质越亲油;反之,LogP值越小,则说明该物质越亲水。
InChI:
The Key: HLVGVJFVAKPFOZ-SDBHATRESA-N

物化性质展开↓

密度:
1.7g/cm3
沸点:
637ºC at 760mmHg
闪点:
339ºC
折射率:
1.69
蒸汽压:
4E-16mmHg at 25°C

合成路线查看所有的合成路线

  • 6979-94-8

    2',3',5'-三乙酰鸟苷

  • ~96%

  • 16321-99-6

    2',3',5'-三-O-乙酰-2-氨基-6-氯嘌呤核苷

  • 2004-07-1

    6-氯鸟嘌呤核苷

  • +

  • 108-24-7

    乙酸酐

  • ~90%

  • 16321-99-6

    2',3',5'-三-O-乙酰-2-氨基-6-氯嘌呤核苷

  • 108-24-7

    乙酸酐

  • +

  • 118-00-3

    鸟嘌呤核苷

  • 16321-99-6

    2',3',5'-三-O-乙酰-2-氨基-6-氯嘌呤核苷

MSDS 展开↓

  2',3',5'-Tri-O-acetyl-2-amino-6-chloropurine Riboside Revision number: 5
  SAFETY DATA SHEET

Section 1. IDENTIFICATION
    2',3',5'-Tri-O-acetyl-2-amino-6-chloropurine Riboside
  Product name:
    

    5
  Revision number:

Section 2. HAZARDS IDENTIFICATION
  GHS classification
    Not classified
  PHYSICAL HAZARDS
    Not classified
  HEALTH HAZARDS
    Not classified
  ENVIRONMENTAL HAZARDS
  GHS label elements, including precautionary statements
    None
  Pictograms or hazard symbols
    No signal word
  Signal word
    None
  Hazard statements
    None
  Precautionary statements:

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
    Substance
  Substance/mixture:
    2',3',5'-Tri-O-acetyl-2-amino-6-chloropurine Riboside
  Components:
    >97.0%(LC)(T)
  Percent:
    16321-99-6
  CAS Number:
    2-Amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine
  Synonyms:
    C16H18ClN5O7
  Chemical Formula:

Section 4. FIRST AID MEASURES
    Remove victim to fresh air and keep at rest in a position comfortable for breathing.
  Inhalation:
    Get medical advice/attention if you feel unwell.
    Remove/Take off immediately all contaminated clothing. Rinse skin with
  Skin contact:
    water/shower. If skin irritation or rash occurs: Get medical advice/attention.
    Rinse cautiously with water for several minutes. Remove contact lenses, if present
  Eye contact:
    and easy to do. Continue rinsing. If eye irritation persists: Get medical
    advice/attention.
    Get medical advice/attention if you feel unwell. Rinse mouth.
  Ingestion:
    A rescuer should wear personal protective equipment, such as rubber gloves and air-
  Protection of first-aiders:
    tight goggles.

Section 5. FIRE-FIGHTING MEASURES
    Dry chemical, foam, water spray, carbon dioxide.
  Suitable extinguishing
  media:
    Take care as it may decompose upon combustion or in high temperatures to
  Specific hazards arising
    generate poisonous fume.
  from the chemical:
  2',3',5'-Tri-O-acetyl-2-amino-6-chloropurine
  Riboside

Section 5. FIRE-FIGHTING MEASURES
  Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
    method according to the surrounding situation is used. Uninvolved persons should
    evacuate to a safe place. In case of fire in the surroundings: Remove movable
    containers if safe to do so.
    When extinguishing fire, be sure to wear personal protective equipment.
  Special protective
  equipment for firefighters:

Section 6. ACCIDENTAL RELEASE MEASURES
    Use personal protective equipment. Keep people away from and upwind of spill/leak.
  Personal precautions,
  protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
  emergency procedures: roping off, etc.
  Environmental precautions: Prevent product from entering drains.
  Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
  containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
  up: appropriate laws and regulations.

Section 7. HANDLING AND STORAGE
  Precautions for safe handling
    Handling is performed in a well ventilated place. Wear suitable protective equipment.
  Technical measures:
    Prevent dispersion of dust. Wash hands and face thoroughly after handling.
    Use a local exhaust if dust or aerosol will be generated.
  Advice on safe handling: Avoid contact with skin, eyes and clothing.
  Conditions for safe storage, including any
  incompatibilities
    Keep container tightly closed. Store in a cool and dark place.
  Storage conditions:
    Store away from incompatible materials such as oxidizing agents.
    Comply with laws.
  Packaging material:

Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
    Install a closed system or local exhaust as possible so that workers should not be
  Engineering controls:
    exposed directly. Also install safety shower and eye bath.
  Personal protective equipment
  Respiratory protection: Dust respirator. Follow local and national regulations.
    Protective gloves.
  Hand protection:
    Safety glasses. A face-shield, if the situation requires.
  Eye protection:
  Skin and body protection: Protective clothing. Protective boots, if the situation requires.

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
    Solid
  Physical state (20°C):
    Crystal- Powder
  Form:
    Slightly pale yellow - Yellow
  Colour:
    No data available
  Odour:
  pH: No data available
  Melting point/freezing point:148°C
    No data available
  Boiling point/range:
    No data available
  Flash point:
  Flammability or explosive
  limits:
    No data available
  Lower:
    No data available
  Upper:
    No data available
  Relative density:
  Solubility(ies):
    No data available
  [Water]
    No data available
  [Other solvents]
  2',3',5'-Tri-O-acetyl-2-amino-6-chloropurine
  Riboside

Section 10. STABILITY AND REACTIVITY
    Stable under proper conditions.
  Chemical stability:
    No special reactivity has been reported.
  Possibility of hazardous
  reactions:
  Incompatible materials: Oxidizing agents
  Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen chloride
  products:

Section 11. TOXICOLOGICAL INFORMATION
    No data available
  Acute Toxicity:
    No data available
  Skin corrosion/irritation:
    No data available
  Serious eye
  damage/irritation:
    No data available
  Germ cell mutagenicity:
  Carcinogenicity:
    No data available
  IARC =
    No data available
  NTP =
    No data available
  Reproductive toxicity:

Section 12. ECOLOGICAL INFORMATION
  Ecotoxicity:
    No data available
  Fish:
    No data available
  Crustacea:
    No data available
  Algae:
  Persistence / degradability: No data available
    No data available
  Bioaccumulative
  potential(BCF):
  Mobility in soil
    No data available
  Log Pow:
    No data available
  Soil adsorption (Koc):
    No data available
  Henry's Law
  constant(PaM3/mol):

Section 13. DISPOSAL CONSIDERATIONS
    Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
    with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
    Observe all federal, state and local regulations when disposing of the substance.

Section 14. TRANSPORT INFORMATION
    Does not correspond to the classification standard of the United Nations
  Hazards Class:
    Not listed
  UN-No:

Section 15. REGULATORY INFORMATION
  Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
  and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
    loading and unloading were prescribed.
  2',3',5'-Tri-O-acetyl-2-amino-6-chloropurine
  Riboside


SECTION 16 - ADDITIONAL INFORMATION
N/A

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